# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3587284 | B | Inhibition of menin-MLL1 interaction (unknown origin) | Homo sapiens | 2 | ALA3585303 | protein format | Scientific Literature | |
2. | ALA3587285 | F | Growth inhibition of human MV4-11 cells | Homo sapiens | 1 | ALA3585303 | cell-based format | Scientific Literature | |
3. | ALA3614558 | B | Inhibition of N-terminal thioredoxin His6-tagged full-length human menin expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in menin interaction with FITC-MBM1 peptide of MLL (4 to 15 residues) by fluorescence polarization assay | Homo sapiens | 9 | ALA3611991 | cell-based format | Scientific Literature | |
4. | ALA4149601 | B | Inhibition of FITC-labelled MLL1 binding to menin (unknown origin) after 120 mins by fluorescence polarization method | Homo sapiens | 1 | ALA4145581 | single protein format | Scientific Literature | |
5. | ALA4262730 | B | Inhibition of full length human menin-MLL1 (4 to 43 residues) (unknown origin) protein-protein interaction after 1 hr by fluorescence polarization assay | Homo sapiens | 2 | ALA4261532 | protein format | Scientific Literature | |
6. | ALA4370538 | B | Inhibition of recombinant human LSD1 (172 to 852 residues) using biotin-labelled H3K4me2 (1 to 24 residues) after 1 hr by TR-FRET assay | Homo sapiens | 18 | ALA4368922 | single protein format | Scientific Literature | |
7. | ALA4370539 | B | Inhibition of full length human menin/FAM-tagged MLL1 (unknown origin) protein-protein interaction after 15 mins by fluorescence polarization assay | Homo sapiens | 18 | ALA4368922 | protein format | Scientific Literature | |
8. | ALA4370540 | B | Inhibition of MAOA (unknown origin) by Promega MAO-Glo assay | Homo sapiens | 18 | ALA4368922 | single protein format | Scientific Literature | |
9. | ALA4370541 | B | Inhibition of MAOB (unknown origin) by Promega MAO-Glo assay | Homo sapiens | 18 | ALA4368922 | single protein format | Scientific Literature | |
10. | ALA4370542 | F | Antiproliferative activity against human MV4-11 cells after 168 hrs by MTS assay | Homo sapiens | 17 | ALA4368922 | cell-based format | Scientific Literature | |
11. | ALA4432623 | B | Inhibition of human recombinant full length menin/MLL1 (unknown origin) interaction using Ac-SRWRFPARPGTGRR-Ahx-Ahx-K-FAM as substrate after 15 mins by fluorescence polarization binding assay | Homo sapiens | 27 | ALA4431355 | protein format | Scientific Literature | |
12. | ALA4432625 | F | Antiproliferative activity against human MV4-11 cells expressing MLL-AF4 after 7 days by MTS assay | Homo sapiens | 15 | ALA4431355 | cell-based format | Scientific Literature | |
13. | ALA4432626 | F | Antiproliferative activity against human K562 cells after 7 days by MTS assay | Homo sapiens | 15 | ALA4431355 | cell-based format | Scientific Literature |