# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3587482 | B | Binding affinity to human OX2 receptor | Homo sapiens | 30 | single protein format | Scientific Literature | ||
2. | ALA3587483 | B | Binding affinity to human OX1 receptor | Homo sapiens | 30 | single protein format | Scientific Literature | ||
3. | ALA3587700 | A | Metabolic stability in rat liver microsomes assessed as extraction ratio at 1 uM measured over 1 hr by LC-MS/MS analysis | Rattus norvegicus | 12 | assay format | Scientific Literature | ||
4. | ALA3587701 | A | Metabolic stability in human liver microsomes assessed as extraction ratio at 1 uM measured over 1 hr by LC-MS/MS analysis | Homo sapiens | 12 | assay format | Scientific Literature | ||
5. | ALA3587702 | B | Inhibition of [3H]-astemizole binding to human ERG expressed in HEK293 cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
6. | ALA3587703 | B | Binding affinity to rat OX2 receptor | Rattus norvegicus | 12 | single protein format | Scientific Literature | ||
7. | ALA3587705 | F | Ex vivo OX2 receptor occupancy in Sprague-Dawley rat brain at 30 mg/kg, po after 30 mins by autoradiographic analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
8. | ALA3587707 | A | Clearance in Sprague-Dawley rat at 10 mg/kg, po and 1 mg/kg, iv | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
9. | ALA3587708 | A | Volume of distribution at steady state in Sprague-Dawley rat at 10 mg/kg, po and 1 mg/kg, iv | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
10. | ALA3587709 | A | Half life in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
11. | ALA3587710 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
12. | ALA3587722 | A | Cmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature |