| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3587481 | P | Chemical stability of the compound assessed as compound remaining at ambient relative humidity at 22 degC after 4 weeks by HPLC analysis | 1 | ALA3585263 | small-molecule physicochemical format | Scientific Literature | ||
| 2. | ALA3587482 | B | Binding affinity to human OX2 receptor | Homo sapiens | 30 | ALA3585263 | single protein format | Scientific Literature | |
| 3. | ALA3587483 | B | Binding affinity to human OX1 receptor | Homo sapiens | 30 | ALA3585263 | single protein format | Scientific Literature | |
| 4. | ALA3587700 | A | Metabolic stability in rat liver microsomes assessed as extraction ratio at 1 uM measured over 1 hr by LC-MS/MS analysis | Rattus norvegicus | 12 | ALA3585263 | assay format | Scientific Literature | |
| 5. | ALA3587701 | A | Metabolic stability in human liver microsomes assessed as extraction ratio at 1 uM measured over 1 hr by LC-MS/MS analysis | Homo sapiens | 12 | ALA3585263 | assay format | Scientific Literature | |
| 6. | ALA3587702 | B | Inhibition of [3H]-astemizole binding to human ERG expressed in HEK293 cells | Homo sapiens | 12 | ALA3585263 | cell-based format | Scientific Literature | |
| 7. | ALA3587703 | B | Binding affinity to rat OX2 receptor | Rattus norvegicus | 12 | ALA3585263 | single protein format | Scientific Literature | |
| 8. | ALA3587706 | F | Ex vivo OX2 receptor occupancy in Sprague-Dawley rat brain at 30 mg/kg, po after 15 mins by autoradiographic analysis | Rattus norvegicus | 3 | ALA3585263 | organism-based format | Scientific Literature | |
| 9. | ALA3587707 | A | Clearance in Sprague-Dawley rat at 10 mg/kg, po and 1 mg/kg, iv | Rattus norvegicus | 5 | ALA3585263 | organism-based format | Scientific Literature | |
| 10. | ALA3587708 | A | Volume of distribution at steady state in Sprague-Dawley rat at 10 mg/kg, po and 1 mg/kg, iv | Rattus norvegicus | 5 | ALA3585263 | organism-based format | Scientific Literature | |
| 11. | ALA3587709 | A | Half life in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 5 | ALA3585263 | organism-based format | Scientific Literature | |
| 12. | ALA3587710 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg | Rattus norvegicus | 5 | ALA3585263 | organism-based format | Scientific Literature | |
| 13. | ALA3587711 | A | Apparent permeability from basolateral to apical side in human Caco2/TC7 cells at 10 uM | Homo sapiens | 3 | ALA3585263 | cell-based format | Scientific Literature | |
| 14. | ALA3587712 | A | Apparent permeability from apical to basolateral side in human Caco2/TC7 cells at 10 uM | Homo sapiens | 3 | ALA3585263 | cell-based format | Scientific Literature | |
| 15. | ALA3587713 | A | Plasma protein binding in human at 1 uM after 6 hrs by equilibrium dialysis method | Homo sapiens | 3 | ALA3585263 | cell-free format | Scientific Literature | |
| 16. | ALA3587714 | A | Plasma protein binding in rat at 1 uM after 6 hrs by equilibrium dialysis method | Rattus norvegicus | 3 | ALA3585263 | cell-free format | Scientific Literature | |
| 17. | ALA3587715 | A | Protein binding in rat brain at 5 uM after 5 hrs by equilibrium dialysis method | Rattus norvegicus | 3 | ALA3585263 | tissue-based format | Scientific Literature | |
| 18. | ALA3587716 | A | Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate by LC-MS/MS analysis | Homo sapiens | 3 | ALA3585263 | assay format | Scientific Literature | |
| 19. | ALA3587717 | A | Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate by LC-MS/MS analysis | Homo sapiens | 1 | ALA3585263 | assay format | Scientific Literature | |
| 20. | ALA3587718 | A | Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate by LC-MS/MS analysis | Homo sapiens | 1 | ALA3585263 | assay format | Scientific Literature |
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