| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3588237 | B | Inhibition of BTK autophosphorylation in human Raji cells after 30 mins by Phos-Y223 Btk HTRF assay | Homo sapiens | 5 | ALA3585313 | cell-based format | Scientific Literature | |
| 2. | ALA3588238 | B | Inhibition of Lck (unknown origin) | Homo sapiens | 6 | ALA3585313 | single protein format | Scientific Literature | |
| 3. | ALA3588239 | A | Hepatic extraction ratio in human liver microsomes at 1 uM up to 30 mins by LC-MS/MS analysis | Homo sapiens | 5 | ALA3585313 | assay format | Scientific Literature | |
| 4. | ALA3588243 | A | Clearance in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 2 | ALA3585313 | organism-based format | Scientific Literature | |
| 5. | ALA3588245 | A | Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv and 4 mg/kg, po | Rattus norvegicus | 2 | ALA3585313 | organism-based format | Scientific Literature | |
| 6. | ALA3588246 | A | Half life in Sprague-Dawley rat at 1 mg/kg, iv and 4 mg/kg, po | Rattus norvegicus | 2 | ALA3585313 | organism-based format | Scientific Literature | |
| 7. | ALA3588247 | A | Oral bioavailability in Sprague-Dawley rat at 4 mg/kg | Rattus norvegicus | 2 | ALA3585313 | organism-based format | Scientific Literature | |
| 8. | ALA3588248 | B | Inhibition of human recombinant ALK2 by LanthaScreen Binding assay | Homo sapiens | 1 | ALA3585313 | single protein format | Scientific Literature | |
| 9. | ALA3588249 | B | Inhibition of human recombinant LIMK1 by LanthaScreen Binding assay | Homo sapiens | 1 | ALA3585313 | single protein format | Scientific Literature | |
| 10. | ALA3588250 | B | Inhibition of human recombinant TNK2 by LanthaScreen Binding assay | Homo sapiens | 1 | ALA3585313 | single protein format | Scientific Literature | |
| 11. | ALA3588251 | F | Antiarthritic activity in po dosed bovine type-2 collagen-induced po dosed female Lewis rat arthritic model assessed as inhibition of paw volume administered as qd starting on day 12 continued through day 21 | Rattus norvegicus | 1 | ALA3585313 | organism-based format | Scientific Literature | |
| 12. | ALA3588252 | F | Antiarthritic activity in po dosed bovine type-2 collagen-induced po dosed female Lewis rat arthritic model assessed as increase in paw volume AUC (0 to 24 hrs) administered as qd starting on day 12 continued through day 21 | Rattus norvegicus | 1 | ALA3585313 | organism-based format | Scientific Literature | |
| 13. | ALA3588253 | B | Inhibition of BTK in human Raji cells after 30 mins by HTRF assay | Homo sapiens | 6 | ALA3585313 | cell-based format | Scientific Literature | |
| 14. | ALA3588254 | A | Clearance in C57/bl6 mouse at 1 mg/kg, iv and 10 mg/kg, po | Mus musculus | 1 | ALA3585313 | organism-based format | Scientific Literature | |
| 15. | ALA3588255 | A | Volume of distribution at steady state in C57/bl6 mouse at 1 mg/kg, iv and 10 mg/kg, po | Mus musculus | 1 | ALA3585313 | organism-based format | Scientific Literature | |
| 16. | ALA3588256 | A | Half life in C57/bl6 mouse at 1 mg/kg, iv and 10 mg/kg, po | Mus musculus | 1 | ALA3585313 | organism-based format | Scientific Literature | |
| 17. | ALA3588257 | A | Oral bioavailability in C57/bl6 mouse at 10 mg/kg | Mus musculus | 1 | ALA3585313 | organism-based format | Scientific Literature | |
| 18. | ALA3588258 | A | Clearance in beagle dog at 1 mg/kg, iv and 10 mg/kg, po | Canis lupus familiaris | 1 | ALA3585313 | organism-based format | Scientific Literature | |
| 19. | ALA3588259 | A | Volume of distribution at steady state in beagle dog at 1 mg/kg, iv and 10 mg/kg, po | Canis lupus familiaris | 1 | ALA3585313 | organism-based format | Scientific Literature | |
| 20. | ALA3588260 | A | Half life in beagle dog at 1 mg/kg, iv and 10 mg/kg, po | Canis lupus familiaris | 1 | ALA3585313 | organism-based format | Scientific Literature |
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