# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3586964 | B | Inhibition of recombinant mouse aurora kinase A expressed in insect Sf9 cells using biotin-GLRRASLG as substrate in presence of [gamma-33P]ATP | Mus musculus | 5 | ALA3585345 | cell-based format | Scientific Literature | |
2. | ALA3586965 | B | Inhibition of aurora kinase A autophosphorylation at T288 in human HCT116 cells by immunofluorescence analysis | Homo sapiens | 5 | ALA3585345 | cell-based format | Scientific Literature | |
3. | ALA3586966 | B | Inhibition of aurora kinase B in human HCT116 cells assessed as inhibition of histone H3 phosphorylation by immunofluorescence analysis | Homo sapiens | 5 | ALA3585345 | cell-based format | Scientific Literature | |
4. | ALA3586967 | F | Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation by BrdU incorporation assay | Homo sapiens | 5 | ALA3585345 | cell-based format | Scientific Literature | |
5. | ALA3586973 | B | Binding affinity to GABAA alpha-1 benzodiazepine binding site (unknown origin) | Homo sapiens | 3 | ALA3585345 | single protein format | Scientific Literature | |
6. | ALA3586987 | A | Ratio of AUC in Sprague-Dawley rat brain to AUC in Sprague-Dawley rat plasma | Rattus norvegicus | 3 | ALA3585345 | cell-free format | Scientific Literature | |
7. | ALA3586988 | A | In vivo binding affinity to GABAA receptor in po dosed Sprague-Dawley rat | Rattus norvegicus | 2 | ALA3585345 | organism-based format | Scientific Literature | |
8. | ALA3586990 | A | AUC (0 to 24 hrs) in po dosed Sprague-Dawley rat | Rattus norvegicus | 3 | ALA3585345 | organism-based format | Scientific Literature | |
9. | ALA3586991 | A | Cmax in po dosed Sprague-Dawley rat | Rattus norvegicus | 3 | ALA3585345 | organism-based format | Scientific Literature | |
10. | ALA3586993 | T | Toxicity in Sprague-Dawley rat assessed as GABAA related effect at maximum tolerated dose, po administered for 7 days | Rattus norvegicus | 2 | ALA3585345 | organism-based format | Scientific Literature |