| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3592345 | B | Inhibition of human recombinant BACE1 using Mca-SEVNLDAEFK-DNP substrate assessed as substrate hydrolysis after 2 hrs by HPLC-FLU analysis | Homo sapiens | 5 | ALA3588858 | single protein format | Scientific Literature | |
| 2. | ALA3592346 | B | Apparent inhibition of human recombinant BACE2 using Mca-SEVNLDAEFK-DNP substrate assessed as substrate hydrolysis after 1 hr by HPLC-FLU analysis | Homo sapiens | 5 | ALA3588858 | single protein format | Scientific Literature | |
| 3. | ALA3592347 | B | Selectivity ratio of Ki(app) for human recombinant BACE2 to Ki for human recombinant BACE1 | Homo sapiens | 5 | ALA3588858 | assay format | Scientific Literature | |
| 4. | ALA3592348 | A | Half life in human serum by HPLC-FLU analysis | Homo sapiens | 4 | ALA3588858 | cell-free format | Scientific Literature | |
| 5. | ALA3592349 | A | Half life in mouse brain by HPLC-FLU analysis | Mus musculus | 4 | ALA3588858 | tissue-based format | Scientific Literature | |
| 6. | ALA3592350 | A | Cytotoxicity against human Caco2 cells assessed as cell viability at 25 to 50 uM after 4 to 24 hrs by MTS assay | Homo sapiens | 4 | ALA3588858 | cell-based format | Scientific Literature | |
| 7. | ALA3592351 | A | Cytotoxicity against human Caco2 cells assessed as cell viability at 25 to 50 uM after 24 hrs by MTS assay | Homo sapiens | 4 | ALA3588858 | cell-based format | Scientific Literature | |
| 8. | ALA3592352 | A | Retention time of the compound in female mouse brain at 0.53 mg/kg, iv by HPLC-FLU analysis | Mus musculus | 1 | ALA3588858 | organism-based format | Scientific Literature | |
| 9. | ALA3592357 | A | Metabolic stability in female mouse serum at 0.53 mg/kg, iv by HPLC-FLU analysis | Mus musculus | 1 | ALA3588858 | organism-based format | Scientific Literature | |
| 10. | ALA3592360 | A | Metabolic stability in Wistar rat brain cortex at 0.53 mg/kg, iv after 2 hrs by HPLC-FLU analysis | Rattus norvegicus | 1 | ALA3588858 | organism-based format | Scientific Literature | |
| 11. | ALA3592361 | A | Metabolic stability in Wistar rat serum at 0.53 mg/kg, iv after 2 hrs by HPLC-FLU analysis | Rattus norvegicus | 1 | ALA3588858 | organism-based format | Scientific Literature |
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