| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3592701 | B | Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after 1.5 hrs by FP competitive inhibition assay | Homo sapiens | 34 | ALA3588842 | single protein format | Scientific Literature | |
| 2. | ALA3592702 | B | Inhibition of N-terminally His6-tagged human beta-catenin (residues 138-686)/C-terminally biotinylated human Tcf4 (residues 7-51) interaction after 45 mins by AlphaScreen competitive inhibition assay | Homo sapiens | 21 | ALA3588842 | single protein format | Scientific Literature | |
| 3. | ALA3592703 | B | Inhibition of interaction of beta-catenin (unknown origin) transfected in Wnt-activated HEK293 cells/Tcf4 assessed as decrease in transactivation of canonical Wnt signaling by TOPflash luciferase reporter assay | Homo sapiens | 11 | ALA3588842 | cell-based format | Scientific Literature | |
| 4. | ALA3592704 | B | Inhibition of beta-catenin/Tcf4 interaction in human SW480 cells assessed as decrease in transactivation of canonical Wnt signaling by TOPflash luciferase reporter assay | Homo sapiens | 3 | ALA3588842 | cell-based format | Scientific Literature | |
| 5. | ALA3592705 | B | Inhibition of beta-catenin (unknown origin) transfected in Wnt-activated HEK293 cells interaction with Tcf4 assessed as decrease in transactivation of canonical Wnt signaling at >= 5 uM by FOPflash luciferase reporter assay | Homo sapiens | 1 | ALA3588842 | cell-based format | Scientific Literature | |
| 6. | ALA3592706 | B | Inhibition of beta-catenin/Tcf4 interaction in human SW480 cells assessed as decrease in transactivation of canonical Wnt signaling at >=5 uM by FOPflash luciferase reporter assay | Homo sapiens | 1 | ALA3588842 | cell-based format | Scientific Literature | |
| 7. | ALA3592707 | F | Cytotoxicity against human SW480 cells assessed as inhibition of cell growth after 72 hrs by MTS assay | Homo sapiens | 12 | ALA3588842 | cell-based format | Scientific Literature | |
| 8. | ALA3592708 | F | Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTS assay | Homo sapiens | 12 | ALA3588842 | cell-based format | Scientific Literature | |
| 9. | ALA3592709 | F | Cytotoxicity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by MTS assay | Homo sapiens | 6 | ALA3588842 | cell-based format | Scientific Literature | |
| 10. | ALA3592710 | F | Decrease in AXIN2 mRNA expression in human SW480 cells after 24 hrs by quantitative real-time PCR analysis | Homo sapiens | 2 | ALA3588842 | cell-based format | Scientific Literature | |
| 11. | ALA3592711 | F | Decrease in cyclin D1 mRNA expression in human SW480 cells after 24 hrs by quantitative real-time PCR analysis | Homo sapiens | 2 | ALA3588842 | cell-based format | Scientific Literature | |
| 12. | ALA3592712 | F | Decrease in c-myc mRNA expression in human SW480 cells after 24 hrs by quantitative real-time PCR analysis | Homo sapiens | 2 | ALA3588842 | cell-based format | Scientific Literature | |
| 13. | ALA3592713 | F | Decrease in AXIN2 mRNA expression in human SW480 cells at 2 uM after 24 hrs by quantitative real-time PCR analysis | Homo sapiens | 1 | ALA3588842 | cell-based format | Scientific Literature | |
| 14. | ALA3592830 | F | Decrease in cyclin D1 mRNA expression in human SW480 cells at 2 uM after 24 hrs by quantitative real-time PCR analysis | Homo sapiens | 1 | ALA3588842 | cell-based format | Scientific Literature | |
| 15. | ALA3592831 | F | Decrease in c-myc mRNA expression in human SW480 cells at 2 uM after 24 hrs by quantitative real-time PCR analysis | Homo sapiens | 1 | ALA3588842 | cell-based format | Scientific Literature | |
| 16. | ALA3592832 | F | Effect on HPRT mRNA expression in human SW480 cells after 24 hrs by quantitative real-time PCR analysis | Homo sapiens | 2 | ALA3588842 | cell-based format | Scientific Literature | |
| 17. | ALA3592833 | F | Decrease in c-myc protein expression in human SW480 cells at 0.5 uM after 24 hrs by western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 1 | ALA3588842 | cell-based format | Scientific Literature | |
| 18. | ALA3592834 | F | Decrease in c-myc protein expression in human SW480 cells at 1 uM after 24 hrs by western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 1 | ALA3588842 | cell-based format | Scientific Literature | |
| 19. | ALA3592835 | F | Decrease in c-myc protein expression in human SW480 cells at 2 uM after 24 hrs by western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 1 | ALA3588842 | cell-based format | Scientific Literature | |
| 20. | ALA3592836 | F | Decrease in cyclin D1 protein expression in human SW480 cells at 0.5 uM after 24 hrs by western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 1 | ALA3588842 | cell-based format | Scientific Literature |
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