| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3591482 | B | Inhibition of FLAG and hexa-histidine tagged full-length human PRMT6 expressed in HEK293F cells pre-incubated for 30 mins before addition of a [3H]SAM and peptide mix | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 2. | ALA3591483 | B | Inhibition of N-terminal GST tagged full-length human PRMT8 expressed in Escherichia coli (BL21(DE3) pre-incubated for 30 mins before addition of a [3H]SAM and peptide mix | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 3. | ALA3591484 | B | Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SAM and peptide mix | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 4. | ALA3591485 | B | Selectivity for FLAG and hexa-histidine tagged full-length human PRMT6 over PRMT3 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 5. | ALA3591486 | B | Selectivity for FLAG and hexa-histidine tagged full-length human PRMT6 over PRMT4 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA3591487 | B | Selectivity for FLAG and hexa-histidine tagged full-length human PRMT6 over PRMT5 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 7. | ALA3591488 | B | Selectivity for FLAG and hexa-histidine tagged full-length human PRMT6 over PRMT7 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 8. | ALA3591489 | B | Selectivity for N-terminal GST tagged full-length human PRMT8 over PRMT3 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA3591490 | B | Selectivity for N-terminal GST tagged full-length human PRMT8 over PRMT4 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA3591491 | B | Selectivity for N-terminal GST tagged full-length human PRMT8 over PRMT5 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA3591650 | B | Selectivity for N-terminal GST tagged full-length human PRMT8 over PRMT7 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA3591651 | B | Selectivity for N-terminal GST tagged full-length human PRMT1 over PRMT3 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA3591652 | B | Selectivity for N-terminal GST tagged full-length human PRMT1 over PRMT4 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA3591653 | B | Selectivity for N-terminal GST tagged full-length human PRMT1 over PRMT5 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA3591654 | B | Selectivity for N-terminal GST tagged full-length human PRMT1 over PRMT7 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA3591655 | F | Effect on PRMT6 expression in human A375 cells transfected with his-tagged PRMT6 at 0.01 to 20 uM incubated for 48 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3591656 | B | Inhibition of his-tagged PRMT6 (unknown origin) expressed in human A375 cells assessed as reduction in H3R2 methylation at 0.01 to 20 uM incubated for 48 hrs by Western blot method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA3591658 | B | Inhibition of PRMT1 in human A375 cells assessed as effect on monomethyl R*GG motif methylation at 0.01 to 20 uM incubated for 48 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3591659 | B | Selectivity index, ratio of IC50 for PRMT1-mediated R*GG motif methylation human A375 cells to IC50 for his-tagged PRMT6 (unknown origin)-mediated H3R2 methylation in human A375 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3591660 | A | Unbound fraction in Sprague-Dawley rat plasma at 1 uM at 37 degC by equilibrium dialysis and LC-MS/MS method | Rattus norvegicus | 1 | cell-free format | Scientific Literature |
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