# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3591341 | B | Displacement of [125I]-CCL2 from human CCR2 expressed in U2OS cells at 1 uM incubated for 150 mins by scintillation spectrometry | Homo sapiens | 14 | ALA3588778 | cell-based format | Scientific Literature | |
2. | ALA3591343 | F | Antagonist activity against human CCR2B expressed in Chem-1 cells assessed as inhibition of human CCL2-induced intracellular calcium flux incubated for 10 mins by Fluo-4 AM dye based intracellular calcium flux assay | Homo sapiens | 15 | ALA3588778 | cell-based format | Scientific Literature | |
3. | ALA3591344 | B | Antagonist activity against mouse CCR2B expressed in human U2OS cells co-expressing beta-arrestin assessed as inhibition of mouse CCL2-induced beta-arrestin recruitment pre-incubated for 10 mins before mouse CCL2 stimulation for 90 mins by luminescence based assay | Mus musculus | 15 | ALA3588778 | cell-based format | Scientific Literature |