| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3591620 | F | Anticonvulsant activity in ip dosed albino Carworth Farms No. 1 mouse measured at 0.25 hrs by maximal electroshock seizure test | Mus musculus | 5 | ALA3588826 | organism-based format | Scientific Literature | |
| 2. | ALA3591627 | F | Anticonvulsant activity in ip dosed albino Carworth Farms No. 1 mouse measured at 0.25 hrs by 6Hz (32 mA) psychomotor seizure test | Mus musculus | 2 | ALA3588826 | organism-based format | Scientific Literature | |
| 3. | ALA3591629 | T | Neurotoxicity in ip dosed albino Carworth Farms No. 1 mouse measured at 0.25 hrs by rotarod test | Mus musculus | 7 | ALA3588826 | organism-based format | Scientific Literature | |
| 4. | ALA3591631 | T | Protective index, ratio of TD50 for neurotoxicity in ip dosed albino Carworth Farms No. 1 mouse to ED50 for anticonvulsant activity in ip dosed MES albino Carworth Farms No. 1 mouse model | Mus musculus | 9 | ALA3588826 | organism-based format | Scientific Literature | |
| 5. | ALA3591637 | F | Anticonvulsant activity in po dosed albino Sprague-Dawley rat measured at 2 hrs by maximal electroshock seizure test | Rattus norvegicus | 2 | ALA3588826 | organism-based format | Scientific Literature | |
| 6. | ALA3591642 | T | Behavioural toxicity in po dosed albino Sprague-Dawley rat measured at 1 hr | Rattus norvegicus | 1 | ALA3588826 | organism-based format | Scientific Literature | |
| 7. | ALA3591644 | T | Protective index, ratio of TD50 for behavioural toxicity in po dosed albino Sprague-Dawley rat to ED50 for anticonvulsant activity in po dosed MES albino Sprague-Dawley rat model | Rattus norvegicus | 6 | ALA3588826 | organism-based format | Scientific Literature | |
| 8. | ALA3591647 | F | Anticonvulsant activity in ip dosed albino Sprague-Dawley rat measured at 2 hrs by maximal electroshock seizure test | Rattus norvegicus | 1 | ALA3588826 | organism-based format | Scientific Literature | |
| 9. | ALA3591784 | T | Behavioural toxicity in ip dosed albino Sprague-Dawley rat measured at 2 hrs | Rattus norvegicus | 1 | ALA3588826 | organism-based format | Scientific Literature | |
| 10. | ALA3591786 | T | Protective index, ratio of TD50 for behavioural toxicity in ip dosed albino Sprague-Dawley rat to ED50 for anticonvulsant activity in ip dosed MES albino Sprague-Dawley rat model | Rattus norvegicus | 5 | ALA3588826 | organism-based format | Scientific Literature | |
| 11. | ALA3591788 | B | Inhibition of voltage-gated sodium channel in rat embryonic cortical neurons assessed as decrease in fraction of current available at 10 uM measured at -50 mV by whole cell patch-clamp electrophysiology | Rattus norvegicus | 2 | ALA3588826 | assay format | Scientific Literature | |
| 12. | ALA3591789 | B | Effect on steady state fast-inactivation of voltage-gated sodium channel in rat embryonic cortical neurons at 10 uM by whole cell patch-clamp electrophysiology | Rattus norvegicus | 2 | ALA3588826 | assay format | Scientific Literature | |
| 13. | ALA3591791 | B | Effect on steady state activation of voltage-gated sodium channel in rat embryonic cortical neurons at 10 uM by whole cell patch-clamp electrophysiology | Rattus norvegicus | 2 | ALA3588826 | assay format | Scientific Literature | |
| 14. | ALA3591944 | B | Frequency-dependent inhibition of voltage-gated sodium channel in rat embryonic cortical neurons assessed as current amplitude at 10 uM measured at holding potential of -80 mV by whole cell patch-clamp electrophysiology | Rattus norvegicus | 7 | ALA3588826 | assay format | Scientific Literature | |
| 15. | ALA3591945 | B | Inhibition of voltage-gated sodium channel in mouse CAD cells assessed as transition of channels to slow-inactivated state by whole cell patch-clamp electrophysiology | Mus musculus | 1 | ALA3588826 | cell-based format | Scientific Literature | |
| 16. | ALA3591946 | B | Inhibition of voltage-gated sodium channel in mouse CAD cells assessed as transition of channels to slow-inactivated state measured at -50 mV by whole cell patch-clamp electrophysiology | Mus musculus | 1 | ALA3588826 | cell-based format | Scientific Literature | |
| 17. | ALA3592060 | B | Inhibition of voltage-gated sodium channel in mouse CAD cells assessed as transition of channels to slow-inactivated state measured at +20 mV by whole cell patch-clamp electrophysiology | Mus musculus | 1 | ALA3588826 | cell-based format | Scientific Literature | |
| 18. | ALA3592061 | B | Inhibition of voltage-gated sodium channel in mouse CAD cells assessed as half-maximal voltage for steady state fast-inactivation at 10 uM by whole cell patch-clamp electrophysiology (Rvb = -69.1 +/-3.6 mV) | Mus musculus | 1 | ALA3588826 | cell-based format | Scientific Literature | |
| 19. | ALA3592062 | B | Effect on steady state activation of voltage-gated sodium channel in mouse CAD cells at 100 nM to 1 uM by whole cell patch-clamp electrophysiology | Mus musculus | 1 | ALA3588826 | cell-based format | Scientific Literature | |
| 20. | ALA3592063 | B | Frequency-dependent inhibition of voltage-gated sodium channel in mouse CAD cells assessed as decrease in current amplitude at 10 uM by whole cell patch-clamp electrophysiology | Mus musculus | 1 | ALA3588826 | cell-based format | Scientific Literature |
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