# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3590982 | F | Cytotoxicity against human BT474 cells assessed as reduction in cell number incubated for 72 hrs | Homo sapiens | 30 | ALA3588752 | cell-based format | Scientific Literature | |
2. | ALA3590983 | A | Cytotoxicity against HMEC cells assessed as reduction in cell number incubated for 72 hrs | Homo sapiens | 30 | ALA3588752 | cell-based format | Scientific Literature | |
3. | ALA3590984 | F | Lysosomotropic activity in human BT474 cells assessed as reduction in lysosomal pH incubated for 24 hrs by lysosomotropy assay | Homo sapiens | 4 | ALA3588752 | cell-based format | Scientific Literature | |
4. | ALA3590985 | B | Inhibition of REV-ERBbeta (unknown origin) expressed in HEK293 cells incubated for 24 hrs assessed as inhibition of receptor-mediated transcriptional repression by REV-ERB luciferase reporter assay | Homo sapiens | 4 | ALA3588752 | cell-based format | Scientific Literature | |
5. | ALA3590986 | F | Inhibition of autophagy in human BT474 cells assessed as increase in LC3-II protein levels at 10 uM by immunoblot method | Homo sapiens | 4 | ALA3588752 | cell-based format | Scientific Literature | |
6. | ALA3590987 | B | Inhibition of REV-ERBbeta in human BT474 cells assessed as reduction in BMAL1 expression at 10 uM incubated for 16 hrs by immunoblot method | Homo sapiens | 4 | ALA3588752 | cell-based format | Scientific Literature | |
7. | ALA3590988 | T | Toxicity against human BT474 cells assessed as reduction in cell number at 10 uM incubated for 16 hrs | Homo sapiens | 4 | ALA3588752 | cell-based format | Scientific Literature | |
8. | ALA4308977 | P | Dissociation constant, pKa of compound | 1 | ALA4308824 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA4308978 | F | Cytotoxicity against human BT474 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 2 | ALA4308824 | cell-based format | Scientific Literature | |
10. | ALA4727680 | B | Antagonist activity at Rev-Erb alpha (unknown origin) by RORE-luciferase reporter assay | Homo sapiens | 1 | ALA4725320 | single protein format | Scientific Literature | |
11. | ALA5250366 | F | Inhibition of autophagy in human BT-474 cells | Homo sapiens | 2 | ALA5247623 | cell-based format | Scientific Literature |