# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3590982 | F | Cytotoxicity against human BT474 cells assessed as reduction in cell number incubated for 72 hrs | Homo sapiens | 30 | ALA3588752 | cell-based format | Scientific Literature | |
2. | ALA3590983 | A | Cytotoxicity against HMEC cells assessed as reduction in cell number incubated for 72 hrs | Homo sapiens | 30 | ALA3588752 | cell-based format | Scientific Literature | |
3. | ALA3590984 | F | Lysosomotropic activity in human BT474 cells assessed as reduction in lysosomal pH incubated for 24 hrs by lysosomotropy assay | Homo sapiens | 4 | ALA3588752 | cell-based format | Scientific Literature | |
4. | ALA3590985 | B | Inhibition of REV-ERBbeta (unknown origin) expressed in HEK293 cells incubated for 24 hrs assessed as inhibition of receptor-mediated transcriptional repression by REV-ERB luciferase reporter assay | Homo sapiens | 4 | ALA3588752 | cell-based format | Scientific Literature | |
5. | ALA3590986 | F | Inhibition of autophagy in human BT474 cells assessed as increase in LC3-II protein levels at 10 uM by immunoblot method | Homo sapiens | 4 | ALA3588752 | cell-based format | Scientific Literature | |
6. | ALA3590987 | B | Inhibition of REV-ERBbeta in human BT474 cells assessed as reduction in BMAL1 expression at 10 uM incubated for 16 hrs by immunoblot method | Homo sapiens | 4 | ALA3588752 | cell-based format | Scientific Literature | |
7. | ALA3590988 | T | Toxicity against human BT474 cells assessed as reduction in cell number at 10 uM incubated for 16 hrs | Homo sapiens | 4 | ALA3588752 | cell-based format | Scientific Literature | |
8. | ALA3590989 | F | Cytotoxicity against human MDA-MB-361 cells assessed as reduction in cell number incubated for 72 hrs | Homo sapiens | 2 | ALA3588752 | cell-based format | Scientific Literature | |
9. | ALA3590990 | F | Cytotoxicity against human SKBR3 cells assessed as reduction in cell number incubated for 72 hrs | Homo sapiens | 2 | ALA3588752 | cell-based format | Scientific Literature | |
10. | ALA3590991 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell number incubated for 72 hrs | Homo sapiens | 2 | ALA3588752 | cell-based format | Scientific Literature | |
11. | ALA3590992 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell number incubated for 72 hrs | Homo sapiens | 2 | ALA3588752 | cell-based format | Scientific Literature | |
12. | ALA3590993 | F | Cytotoxicity against human LNCAP cells assessed as reduction in cell number incubated for 72 hrs | Homo sapiens | 2 | ALA3588752 | cell-based format | Scientific Literature | |
13. | ALA3590994 | F | Potency index, ratio of IC50 for chloroquine to IC50 for test compound against human HepG2 cells assessed as reduction in cell number incubated for 72 hrs | Homo sapiens | 1 | ALA3588752 | cell-based format | Scientific Literature | |
14. | ALA3590995 | F | Potency index, ratio of IC50 for chloroquine to IC50 for test compound against human LNCAP cells assessed as reduction in cell number incubated for 72 hrs | Homo sapiens | 1 | ALA3588752 | cell-based format | Scientific Literature | |
15. | ALA3590999 | B | Inhibition of REV-ERBbeta in human SKBR3 cells assessed as reduction in BMAL1 expression at 10 uM incubated for 16 hrs by immunoblot method | Homo sapiens | 1 | ALA3588752 | cell-based format | Scientific Literature | |
16. | ALA3591151 | B | Inhibition of REV-ERBbeta in human HepG2 cells assessed as reduction in BMAL1 expression at 10 uM incubated for 16 hrs by immunoblot method | Homo sapiens | 1 | ALA3588752 | cell-based format | Scientific Literature | |
17. | ALA3591152 | B | Inhibition of REV-ERBbeta in human LNCAP cells assessed as reduction in BMAL1 expression at 10 uM incubated for 16 hrs by immunoblot method | Homo sapiens | 1 | ALA3588752 | cell-based format | Scientific Literature | |
18. | ALA3591153 | F | Inhibition of autophagy in human SKBR3 cells assessed as increase in GFP/RFP/LC3 chimera protein levels at 30 uM incubated for 4 hrs by fluorescent microscopy | Homo sapiens | 1 | ALA3588752 | cell-based format | Scientific Literature | |
19. | ALA3591154 | F | Inhibition of autophagy in human HepG2 cells assessed as increase in GFP/RFP/LC3 chimera protein levels at 30 uM incubated for 4 hrs by fluorescent microscopy | Homo sapiens | 1 | ALA3588752 | cell-based format | Scientific Literature | |
20. | ALA3591155 | F | Inhibition of autophagy in human LNCAP cells assessed as increase in GFP/RFP/LC3 chimera protein levels at 30 uM incubated for 4 hrs by fluorescent microscopy | Homo sapiens | 1 | ALA3588752 | cell-based format | Scientific Literature |