# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3595275 | Binding | Inhibition of human TNKS2 (956 to 1161 and 873 to 1161) using 500 nM NAD substrate after 20 mins incubation by fluorescence assay | Homo sapiens | 33 | ALA3593161 | single protein format | Scientific Literature | |
2. | ALA3595276 | Binding | Inhibition of TNKS-2 (unknown origin) in HEK293 cells assessed as disruption of Wnt3a/beta-catenin signaling after 24 hrs by STF- cell-based luciferase reporter assay | Homo sapiens | 4 | ALA3593161 | cell-based format | Scientific Literature | |
3. | ALA3595277 | Binding | Inhibition of TNKS-2 (unknown origin) in HEK293 cells assessed as disruption of Wnt3a/beta-catenin signaling at 10 uM after 24 hrs by STF- cell-based luciferase reporter assay | Homo sapiens | 3 | ALA3593161 | cell-based format | Scientific Literature | |
4. | ALA3595278 | Binding | Inhibition of beta-galactosidase (unknown origin) at 2.5 to 10 uM | Not specified | 4 | ALA3593161 | assay format | Scientific Literature | |
5. | ALA3595279 | ADME | Cytotoxicity against HEK293 cells assessed as cell viability at 2.5 to 10 uM | Homo sapiens | 4 | ALA3593161 | cell-based format | Scientific Literature | |
6. | ALA3595280 | Binding | Inhibition of human TNKS1 (1030 to 1317) using NAD substrate after 20 mins incubation by fluorescence assay | Homo sapiens | 4 | ALA3593161 | single protein format | Scientific Literature | |
7. | ALA3595281 | Binding | Inhibition of full-length human ARTD1 using 500 nM NAD substrate after 1 hr incubation | Homo sapiens | 4 | ALA3593161 | single protein format | Scientific Literature | |
8. | ALA3595282 | Binding | Inhibition of full-length human ARTD2 using 500 nM NAD substrate after 3 hrs incubation | Homo sapiens | 4 | ALA3593161 | single protein format | Scientific Literature | |
9. | ALA3595283 | Binding | Inhibition of full-length human ARTD3 using 500 nM NAD substrate after 1 hrs incubation | Homo sapiens | 4 | ALA3593161 | single protein format | Scientific Literature | |
10. | ALA3595284 | Binding | Inhibition of human ARTD4 (250 to 565) using 500 nM NAD substrate after 2.5 hrs incubation | Homo sapiens | 4 | ALA3593161 | single protein format | Scientific Literature | |
11. | ALA3595285 | Binding | Inhibition of human ARTD7 (460 to 656) using 250 nM NAD substrate after 2 hrs incubation | Homo sapiens | 2 | ALA3593161 | single protein format | Scientific Literature | |
12. | ALA3595286 | Binding | Inhibition of human ARTD10 (809 to 1017) using 500 nM NAD substrate after 2.5 hrs incubation | Homo sapiens | 2 | ALA3593161 | single protein format | Scientific Literature |