# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA689641 | F | In vitro concentration required to induce apoptosis in HL60 cells | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
2. | ALA689647 | F | In vitro inhibitory concentration against proliferation of HL60 cells | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
3. | ALA990713 | F | Antiproliferative activity against human CNE1 cells after 72 hrs by MTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
4. | ALA990714 | F | Antiproliferative activity against human CNE2 cells after 72 hrs by MTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
5. | ALA1175840 | B | Inhibition of human aromatase at 20 ug/ml preincubated with NADP+ for 10 mins before substrate addition measured after 30 mins | Homo sapiens | 44 | single protein format | Scientific Literature | ||
6. | ALA1175841 | B | Inhibition of human aromatase at IC50 concentration preincubated with NADP+ for 10 mins before substrate addition measured after 30 mins | Homo sapiens | 26 | single protein format | Scientific Literature | ||
7. | ALA1175842 | B | Inhibition of human aromatase preincubated with NADP+ for 10 mins before substrate addition measured after 30 mins | Homo sapiens | 44 | single protein format | Scientific Literature | ||
8. | ALA1175843 | B | Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) by UV-vis microplate reader analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
9. | ALA1175844 | B | Inhibition of human aromatase assessed per mg of protein at IC50 concentration preincubated with NADP+ for 10 mins before substrate addition measured after 30 mins | Homo sapiens | 26 | single protein format | Scientific Literature | ||
10. | ALA1248326 | F | Induction of apoptosis in human HT-29 cells assessed as caspase3 activity | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
11. | ALA1248327 | F | Induction of apoptosis in human HT-29 cells assessed as PARP cleavage | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
12. | ALA1248328 | F | Reduction of proliferating cell nuclear antigen level in human HT-29 cells by immunohistochemistry analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
13. | ALA1248451 | F | Up-regulation of p27 expression level in human HT-29 cells by Western blotting | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
14. | ALA1248452 | F | Up-regulation of p27 expression level in human HT-29 cells by immunohistochemistry analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
15. | ALA1248453 | A | Drug level in SCID mouse serum at 10 mg/kg, ip by GC-MS analysis | Mus musculus | 6 | organism-based format | Scientific Literature | ||
16. | ALA1248454 | F | Antitumor activity against human HT-29 cells xenografted in SCID mouse assessed as reduction tumor volume at 10 mg/kg, ip qd for 3 weeks (Rvb = 1087 +/- 138.9 mm'3) | Homo sapiens | 6 | organism-based format | Scientific Literature | ||
17. | ALA1248455 | F | Antitumor activity against human HT-29 cells xenografted in SCID mouse assessed as reduction tumor weight at 10 mg/kg, ip qd for 3 weeks (Rvb = 0.72 +/- 0.1 g) | Homo sapiens | 6 | organism-based format | Scientific Literature | ||
18. | ALA1248456 | T | Toxicity in SCID mouse assessed as effect on body weight at 10 mg/kg, ip qd for 3 weeks (Rvb = 20.4 +/- 0.4 g) | Mus musculus | 6 | organism-based format | Scientific Literature | ||
19. | ALA1248457 | F | Reduction of proliferating cell nuclear antigen level in human HT-29 cells by Western blotting | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
20. | ALA1248458 | F | Cytotoxicity against human HT-29 cells after 3 days by [3H]thymidine incorporation assay | Homo sapiens | 27 | cell-based format | Scientific Literature |