# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3602684 | B | Inhibition of Influenza A/Perto Rico/8/34 (PR8) (H1N1) PA N-terminal domain (1 to 197) endonuclease activity expressed in Escherichia coli Rosetta (DE3) using (6-FAM)-AAT CGC AGG CAG CAC TC-(BHQ-1) as substrate measured every 50 secs for 30 mins by FRET assay | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 3 | ALA3600365 | assay format | Scientific Literature | |
2. | ALA3602685 | F | Antiviral activity against Influenza virus infected in MDCK cells assessed as viral RNA content incubated with cells for 30 mins prior to addition of 30 mins preincubated virus-compound mixture for 1 hr followed by 3 times compound washout and again cultured in compound containing virus growth medium for 24 hrs by RT-PCR analysis | unidentified influenza virus | 3 | ALA3600365 | organism-based format | Scientific Literature | |
3. | ALA3602686 | A | Cytotoxicity against MDCK cells after 24 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Canis lupus familiaris | 3 | ALA3600365 | cell-based format | Scientific Literature | |
4. | ALA3602687 | B | Inhibition of Influenza A/Perto Rico/8/34 (PR8) (H1N1) PAN (1 to 197) endonuclease activity expressed in Escherichia coli Rosetta (DE3) using M13mp18 as substrate at 100 uM after 60 mins by agarose gel elctrophoresis | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 3 | ALA3600365 | assay format | Scientific Literature |