# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3603311 | Binding | Inhibition of TTK (unknown origin) by LanthaScreen assay | Homo sapiens | 6 | ALA3600288 | single protein format | Scientific Literature | |
2. | ALA3603314 | Binding | Selectivity ratio of IC50 for JAK1 (unknown origin) to IC50 for JAK3 (unknown origin) | Homo sapiens | 3 | ALA3600288 | assay format | Scientific Literature | |
3. | ALA3603315 | Binding | Selectivity ratio of IC50 for JAK2 (unknown origin) to IC50 for JAK3 (unknown origin) | Homo sapiens | 3 | ALA3600288 | assay format | Scientific Literature | |
4. | ALA3603316 | Binding | Selectivity ratio of IC50 for TYK2 (unknown origin) to IC50 for JAK3 (unknown origin) | Homo sapiens | 2 | ALA3600288 | assay format | Scientific Literature | |
5. | ALA3603318 | Binding | Inhibition of JAK1 (unknown origin) by Z'-Lyte assay | Homo sapiens | 7 | ALA3600288 | single protein format | Scientific Literature | |
6. | ALA3603319 | Binding | Inhibition of JAK2 (unknown origin) by Z'-Lyte assay | Homo sapiens | 7 | ALA3600288 | single protein format | Scientific Literature | |
7. | ALA3603320 | Binding | Inhibition of TYK2 (unknown origin) by Z'-Lyte assay | Homo sapiens | 4 | ALA3600288 | single protein format | Scientific Literature | |
8. | ALA3603322 | Binding | Selectivity ratio of IC50 for BTK (unknown origin) to IC50 for JAK3 (unknown origin) | Homo sapiens | 2 | ALA3600288 | assay format | Scientific Literature | |
9. | ALA3603323 | Binding | Selectivity ratio of IC50 for ITK (unknown origin) to IC50 for JAK3 (unknown origin) | Homo sapiens | 2 | ALA3600288 | assay format | Scientific Literature | |
10. | ALA3603326 | Binding | Inhibition of JAK3 (unknown origin) by Z'-Lyte assay | Homo sapiens | 72 | ALA3600288 | single protein format | Scientific Literature | |
11. | ALA3603327 | Functional | Antiproliferative activity against mouse BA/F3 cells expressing TEL-JAK1 after 72 hrs by cell titer glo assay | Mus musculus | 65 | ALA3600288 | cell-based format | Scientific Literature | |
12. | ALA3603328 | Functional | Antiproliferative activity against mouse BA/F3 cells expressing TEL-JAK2 after 72 hrs by cell titer glo assay | Mus musculus | 65 | ALA3600288 | cell-based format | Scientific Literature | |
13. | ALA3603329 | Functional | Antiproliferative activity against mouse BA/F3 cells expressing TEL-JAK3 after 72 hrs by cell titer glo assay | Mus musculus | 71 | ALA3600288 | cell-based format | Scientific Literature | |
14. | ALA3603330 | Functional | Antiproliferative activity against mouse BA/F3 cells expressing TYK2 E957D mutant after 72 hrs by cell titer glo assay | Mus musculus | 64 | ALA3600288 | cell-based format | Scientific Literature | |
15. | ALA3603331 | Functional | Antiproliferative activity against mouse BA/F3 cells expressing TEL-ABL after 72 hrs by cell titer glo assay | Mus musculus | 64 | ALA3600288 | cell-based format | Scientific Literature | |
16. | ALA3603332 | ADME | Half life in mouse liver microsomes | Mus musculus | 34 | ALA3600288 | assay format | Scientific Literature | |
17. | ALA3603333 | Binding | Selectivity ratio of IC50 for TTK (unknown origin) to IC50 for JAK3 (unknown origin) | Homo sapiens | 3 | ALA3600288 | assay format | Scientific Literature | |
18. | ALA3603334 | Functional | Selectivity ratio of IC50 for mouse BA/F3 cells expressing TEL-JAK1 to IC50 for mouse BA/F3 cells expressing TEL-JAK3 | Mus musculus | 1 | ALA3600288 | cell-based format | Scientific Literature | |
19. | ALA3603335 | Functional | Selectivity ratio of IC50 for mouse BA/F3 cells expressing TEL-JAK2 to IC50 for mouse BA/F3 cells expressing TEL-JAK3 | Mus musculus | 1 | ALA3600288 | cell-based format | Scientific Literature | |
20. | ALA3603336 | Functional | Selectivity ratio of IC50 for mouse BA/F3 cells expressing TYK2 E957D mutant to IC50 for mouse BA/F3 cells expressing TEL-JAK3 | Mus musculus | 1 | ALA3600288 | cell-based format | Scientific Literature |