# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3603417 | Binding | Inhibition of human IRAK4 (unknown origin) | Homo sapiens | 32 | ALA3600286 | single protein format | Scientific Literature | |
2. | ALA3603418 | Binding | Inhibition of FLT3 (unknown origin) | Homo sapiens | 3 | ALA3600286 | single protein format | Scientific Literature | |
3. | ALA3603419 | Binding | Inhibition of MINK1 (unknown origin) | Homo sapiens | 2 | ALA3600286 | single protein format | Scientific Literature | |
4. | ALA3603420 | Binding | Inhibition of TRKB (unknown origin) | Homo sapiens | 2 | ALA3600286 | single protein format | Scientific Literature | |
5. | ALA3603421 | Binding | Inhibition of LRRK2 (unknown origin) | Homo sapiens | 2 | ALA3600286 | single protein format | Scientific Literature | |
6. | ALA3603422 | Binding | Inhibition of LCK (unknown origin) | Homo sapiens | 1 | ALA3600286 | single protein format | Scientific Literature | |
7. | ALA3603423 | Binding | Inhibition of CLK2 (unknown origin) | Homo sapiens | 2 | ALA3600286 | single protein format | Scientific Literature | |
8. | ALA3603426 | Binding | Inhibition of IRAK4-dependent TLR4 signaling in human THP1-XBlue cells containing NF-kappaB-inducible SEAP reporter gene assessed as inhibition of LPS-EK-induced TLR4 activation incubated at 37 degC for 1 hr by spectrophotometry | Homo sapiens | 7 | ALA3600286 | cell-based format | Scientific Literature | |
9. | ALA3603427 | Binding | Inhibition of TNFR in human THP1-XBlue cells containing NF-kappaB-inducible SEAP reporter gene assessed as inhibition of TNFalpha-induced TNFR activation incubated at 37 degC for 1 hr by spectrophotometry | Homo sapiens | 7 | ALA3600286 | cell-based format | Scientific Literature | |
10. | ALA3603428 | ADME | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 7 | ALA3600286 | single protein format | Scientific Literature | |
11. | ALA3603429 | ADME | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 7 | ALA3600286 | single protein format | Scientific Literature | |
12. | ALA3603430 | ADME | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 7 | ALA3600286 | single protein format | Scientific Literature | |
13. | ALA3603431 | Physicochemical | Solubility in pH 7 solution | 7 | ALA3600286 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA3603432 | Binding | Potency index, ratio of IC50 for inhibition of IRAK4-dependent TLR4 signaling in human THP1-XBlue cells containing NF-kappaB-inducible SEAP reporter gene to IC50 for human IRAK4 (unknown origin) | Homo sapiens | 7 | ALA3600286 | cell-based format | Scientific Literature | |
15. | ALA3603433 | ADME | Apparent permeability in pig LLC-PK1 cells | Sus scrofa | 7 | ALA3600286 | cell-based format | Scientific Literature |