# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3603281 | A | Cytotoxicity against mouse HT22 cells assessed as cell viability at 30 uM after 24 hrs by MTT assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
2. | ALA3603282 | F | Neuroprotective activity in mouse HT22 cells assessed as protection against glutamate-induced cell death at 1 to 30 uM pretreated 30 mins before glutamate challenge measured after 24 hrs by MTT assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
3. | ALA3603283 | F | Neuroprotective activity in mouse HT22 cells assessed as decrease of glutamate-induced increase in LDH level at 10 to 30 uM pretreated 30 mins before glutamate challenge measured after 24 hrs | Mus musculus | 6 | cell-based format | Scientific Literature | ||
4. | ALA3603284 | F | Neuroprotective activity in mouse HT22 cells assessed as protection against glutamate-induced cell death pretreated 30 mins before glutamate challenge measured after 24 hrs by MTT assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
5. | ALA3603285 | F | Neuroprotective activity in mouse HT22 cells assessed as protection against glutamate-induced change in cell morphology at 1 to 30 uM pretreated 30 mins before glutamate challenge measured after 24 hrs by MTT assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
6. | ALA3603286 | A | Cytotoxicity against mouse HT22 cells assessed as induction of cell proliferation at 30 uM after 24 hrs by MTT assay | Mus musculus | 5 | cell-based format | Scientific Literature | ||
7. | ALA3603287 | F | Neuroprotective activity in mouse HT22 cells assessed as decrease of glutamate-induced ROS production at 30 uM pretreated 30 mins before glutamate challenge measured after 12 hrs using H2DCF-DA staining by fluorescence assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
8. | ALA3603288 | F | Neuroprotective activity in mouse HT22 cells assessed as decrease of glutamate-induced decrease in Nrf2/HO-1 protein expression at 30 uM pretreated 30 mins before glutamate challenge measured after 12 hrs by Western blotting assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
9. | ALA3603289 | F | Effect on Nrf2/HO-1 protein expression in mouse HT22 cells at 30 uM after 24 hrs by Western blotting assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
10. | ALA3603290 | F | Neuroprotective activity in mouse HT22 cells assessed as decrease of glutamate-induced decrease in Bcl-2 protein expression at 30 uM pretreated 30 mins before glutamate challenge measured after 12 hrs by Western blotting assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
11. | ALA3866623 | B | Antagonist activity at human EGFP-fused CCR3 expressed in mouse L1.2 cells assessed as inhibition of CCL11-induced chemotaxis at 1 uM measured after 1.5 hrs by PicoGreen dsDNA reagent-based assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
12. | ALA4022455 | B | Inhibition of Streptococcus pneumoniae sialidase NanB using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET assay | Streptococcus pneumoniae | 13 | assay format | Scientific Literature | ||
13. | ALA4022456 | B | Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET assay | Streptococcus pneumoniae | 13 | single protein format | Scientific Literature | ||
14. | ALA4022457 | B | Noncompetitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by Lineweaver-Burk plot/Dixon plot analysis | Streptococcus pneumoniae | 8 | single protein format | Scientific Literature | ||
15. | ALA4022459 | B | Inhibition of Streptococcus pneumoniae sialidase NanC using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET assay | Streptococcus pneumoniae | 12 | assay format | Scientific Literature |