# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3607749 | B | Inhibition of human CD38 extracellular domain expressed in Pichia pastoris using CHAPS and NAD by colorimetric-based assay | Homo sapiens | 71 | ALA3603832 | assay format | Scientific Literature | |
2. | ALA3607750 | B | Inhibition of mouse CD38 | Mus musculus | 2 | ALA3603832 | single protein format | Scientific Literature | |
3. | ALA3607751 | A | Permeability in pH 7.4 buffer after 3 hrs by HPLC with UV detection based artificial membrane permeability assay | 8 | ALA3603832 | assay format | Scientific Literature | ||
4. | ALA3607752 | P | Solubility in FaSSIF | 8 | ALA3603832 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA3607753 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 8 | ALA3603832 | single protein format | Scientific Literature | |
6. | ALA3607754 | A | Half life in mouse liver S9 fraction | Mus musculus | 8 | ALA3603832 | subcellular format | Scientific Literature | |
7. | ALA3607755 | B | Inhibition of human ERG | Homo sapiens | 8 | ALA3603832 | single protein format | Scientific Literature | |
8. | ALA3607756 | A | Terminal half life in mouse | Mus musculus | 8 | ALA3603832 | organism-based format | Scientific Literature | |
9. | ALA3607757 | A | Clearance in mouse | Mus musculus | 8 | ALA3603832 | organism-based format | Scientific Literature | |
10. | ALA3607758 | A | Volume of distribution at steady state in mouse | Mus musculus | 8 | ALA3603832 | organism-based format | Scientific Literature | |
11. | ALA3607759 | A | Oral bio availability in mouse | Mus musculus | 8 | ALA3603832 | organism-based format | Scientific Literature | |
12. | ALA3607760 | A | Dose normalized AUC in mouse | Mus musculus | 8 | ALA3603832 | organism-based format | Scientific Literature | |
13. | ALA3607761 | F | Increase in NAD level in DIO mouse liver at 30 mg/kg after 2 hrs by reverse-phase chromatography relative to control | Mus musculus | 2 | ALA3603832 | organism-based format | Scientific Literature | |
14. | ALA3607762 | F | Increase in NAD level in DIO mouse liver at 30 mg/kg after 6 hrs by reverse-phase chromatography relative to control | Mus musculus | 2 | ALA3603832 | organism-based format | Scientific Literature | |
15. | ALA3607763 | F | Increase in NAD level in DIO mouse gastrocnemius at 30 mg/kg after 2 hrs by reverse-phase chromatography relative to control | Mus musculus | 2 | ALA3603832 | organism-based format | Scientific Literature | |
16. | ALA3607764 | F | Increase in NAD level in DIO mouse gastrocnemius at 30 mg/kg after 6 hrs by reverse-phase chromatography relative to control | Mus musculus | 2 | ALA3603832 | organism-based format | Scientific Literature | |
17. | ALA4222828 | B | Inhibition of human ERG | Homo sapiens | 3 | ALA4219173 | single protein format | Scientific Literature | |
18. | ALA4222829 | B | Inhibition of recombinant human CD38 extracellular domain expressed in Pichia pastoris using NAD as substrate pretreated for 30 mins followed by substrate addition measured after 15 to 45 mins | Homo sapiens | 41 | ALA4219173 | assay format | Scientific Literature | |
19. | ALA4222830 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 3 | ALA4219173 | single protein format | Scientific Literature | |
20. | ALA4222838 | P | Lipophilicity, log D of the compound by chromatographic method | 2 | ALA4219173 | small-molecule physicochemical format | Scientific Literature |