# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3607864 | Functional | Cytotoxicity against human SB2 cells after 48 hrs by CellTiter-Blue assay | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
2. | ALA3607865 | Binding | Inhibition of human ATX phosphodiesterase expressed in Sf9 cells assessed as hydrolysis of FS-3 measured after 5 to 25 mins by fluorescence assay | Homo sapiens | 3 | ALA3603761 | cell-based format | Scientific Literature | |
3. | ALA3607867 | Binding | Inhibition of human ATX phosphodiesterase expressed in Sf9 cells assessed as hydrolysis of FS-3 preincubated for 2 mins before substrate addition measured after 5 to 25 mins by fluorescence assay | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
4. | ALA3607868 | Binding | Irreversible inhibition of human ATX phosphodiesterase activity expressed in Sf9 cells assessed as hydrolysis of FS-3 preincubated for 2 mins before substrate addition measured 1000 fold dilution by fluorescence assay | Homo sapiens | 2 | ALA3603761 | cell-based format | Scientific Literature | |
5. | ALA3607869 | Functional | Cytotoxicity against human PC3 cells after 48 hrs by CellTiter-Blue assay | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
6. | ALA3607870 | Functional | Cytotoxicity against human OVCAR3 cells after 48 hrs by CellTiter-Blue assay | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
7. | ALA3607871 | Functional | Cytotoxicity against human HT-29 cells after 48 hrs by CellTiter-Blue assay | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
8. | ALA3607872 | Functional | Cytotoxicity against human MeWo cells after 48 hrs by CellTiter-Blue assay | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
9. | ALA3607873 | Functional | Cytotoxicity against human MDA-MB-231 cells after 48 hrs by CellTiter-Blue assay | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
10. | ALA3607874 | Functional | Cytotoxicity against human SKOV3 cells after 48 hrs by CellTiter-Blue assay | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
11. | ALA3607875 | Functional | Inhibition of cell migration in human MDA-MB-231 cells assessed as gap closure distance at 5 uM after 24 hrs by wound healing assay | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
12. | ALA3607876 | Functional | Inhibition of cell migration in human OVCAR3 cells assessed as gap closure distance at 5 uM after 24 hrs by wound healing assay | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
13. | ALA3607877 | Functional | Inhibition of cell migration in human SKOV3 cells assessed as gap closure distance at 5 uM after 24 hrs by wound healing assay | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
14. | ALA3607878 | Functional | Inhibition of cell migration in human MeWo cells assessed as gap closure distance at 5 uM after 24 hrs by wound healing assay | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
15. | ALA3607879 | Functional | Inhibition of cell migration in human MDA-MB-231 cells assessed as gap closure distance at 5 uM after 24 hrs by wound healing assay in presence of 1 uM of LPA | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
16. | ALA3607880 | Functional | Inhibition of cell migration in human OVCAR3 cells assessed as gap closure distance at 5 uM after 24 hrs by wound healing assay in presence of 1 uM of LPA | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
17. | ALA3607881 | Functional | Inhibition of cell migration in human SKOV3 cells assessed as gap closure distance at 5 uM after 24 hrs by wound healing assay in presence of 1 uM of LPA | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
18. | ALA3607882 | Functional | Inhibition of cell migration in human MeWo cells assessed as gap closure distance at 5 uM after 24 hrs by wound healing assay in presence of 1 uM of LPA | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
19. | ALA3607883 | Functional | Cytotoxicity against human MeWo cells assessed as reduction of cell viability after 48 hrs by CellTiter-Blue assay | Homo sapiens | 2 | ALA3603761 | cell-based format | Scientific Literature | |
20. | ALA3607884 | Toxicity | Toxicity in human MeWo cells xenografted athymic nude mouse assessed as severe dehydration at 50 mg/kg, ip administered every other day of 21 days post tumor cell injection measured on day 45 | Mus musculus | 1 | ALA3603761 | organism-based format | Scientific Literature |