| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3610070 | B | Binding affinity to human recombinant NK3R by radioligand binding assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 2. | ALA3610071 | B | Antagonist activity against human recombinant NK3R expressed in CHO cells by aequorin functional assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 3. | ALA3610072 | P | Distribution coefficient, log D of the compound at pH 7.4 | 14 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA3610073 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 5. | ALA3610074 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 6. | ALA3610075 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 7. | ALA3610076 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 8. | ALA3610077 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 9. | ALA3610078 | B | Inhibition of human ERG | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 10. | ALA3610089 | A | Apparent permeability from apical to basolateral side in human Caco2 cells | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 11. | ALA3610090 | A | Apparent permeability from basolateral to apical side in human Caco2 cells | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 12. | ALA3610091 | A | Efflux ratio in human Caco2 cells | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 13. | ALA3610092 | A | Unbound fraction in rat plasma after 60 mins | Rattus norvegicus | 8 | cell-free format | Scientific Literature | ||
| 14. | ALA3610094 | A | Unbound fraction in rat brain at 1 mg/kg after 60 mins | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 15. | ALA3610095 | A | Free plasma concentration in rat after 60 mins | Rattus norvegicus | 8 | cell-free format | Scientific Literature | ||
| 16. | ALA3610097 | A | Free drug concentration in rat brain at 1 mg/kg after 60 mins | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 17. | ALA3610098 | A | Ratio of unbound drug concentration in brain to plasma of rat at 1 mg/kg after 60 mins | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 18. | ALA3610099 | A | Total clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 19. | ALA3610101 | A | Volume of distribution at steady state in rat at 1 mg/kg, iv | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 20. | ALA3610103 | A | Half life in rat at 1 mg/kg, iv | Rattus norvegicus | 8 | organism-based format | Scientific Literature |
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