# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3611102 | Binding | Inhibition of liver delta-5 desaturase (unknown origin) | Homo sapiens | 26 | ALA3608212 | assay format | Scientific Literature | |
2. | ALA3611103 | ADME | Plasma concentration in mouse at 30 mg/kg, po after 0.5 hrs by LC/MS-MS analysis | Mus musculus | 4 | ALA3608212 | organism-based format | Scientific Literature | |
3. | ALA3611104 | ADME | Plasma concentration in mouse at 60 mg/kg, po after 0.5 hrs by LC/MS-MS analysis | Mus musculus | 1 | ALA3608212 | organism-based format | Scientific Literature | |
4. | ALA3611105 | ADME | Ratio of plasma concentration in mouse at 30 mg/kg, po after 0.5 hrs to IC50 for liver delta-5 desaturase (unknown origin) | 4 | ALA3608212 | organism-based format | Scientific Literature | ||
5. | ALA3611106 | ADME | Ratio of plasma concentration in mouse at 60 mg/kg, po after 0.5 hrs to IC50 for liver delta-5 desaturase (unknown origin) | 1 | ALA3608212 | organism-based format | Scientific Literature | ||
6. | ALA3611107 | Functional | In vivo inhibition of delta-5 desaturase in mouse liver assessed as conversion of [14C]-DGLA to [14C]-arachidonic acid at 30 mg/kg, po after 2.5 hrs by TLC analysis relative to control | Mus musculus | 4 | ALA3608212 | organism-based format | Scientific Literature | |
7. | ALA3611108 | Functional | In vivo inhibition of delta-5 desaturase in mouse liver assessed as conversion of [14C]-DGLA to [14C]-arachidonic acid at 60 mg/kg, po after 2.5 hrs by TLC analysis relative to control | Mus musculus | 1 | ALA3608212 | organism-based format | Scientific Literature |