| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3611616 | B | Antagonist activity at Kv1.3 in human whole blood assessed as inhibition of thapsigargin-induced IL-2 secretion incubated for 30 prior to thapsigargin induction measured after 48 hrs by electrochemilluminescent immunoassay | Homo sapiens | 143 | single protein format | Scientific Literature | ||
| 2. | ALA3611617 | B | Antagonist activity at Kv1.3 in human whole blood assessed as inhibition of thapsigargin-induced IFN-gamma secretion incubated for 30 prior to thapsigargin induction measured after 48 hrs by electrochemilluminescent immunoassay | Homo sapiens | 143 | single protein format | Scientific Literature | ||
| 3. | ALA3611620 | B | Antagonist activity at human Kv1.3 expressed in CHOK1 cells assessed as inhibition of potassium currents by manual whole-cell patch clamp electrophysiology assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA3611621 | B | Antagonist activity at human Kv1.1 expressed in HEK293 cells assessed as inhibition of potassium currents by manual whole-cell patch clamp electrophysiology assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3611623 | B | Selectivity ratio of IC50 for human Kv1.1 expressed in HEK293 cells by manual whole-cell patch clamp electrophysiology assay to IC50 for human Kv1.3 expressed in CHOK1 cells by manual whole-cell patch clamp electrophysiology assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3611733 | B | Displacement of [125I]-ChTX from mouse Kv1.3 after 20 mins by scintillation counting analysis | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 7. | ALA3611734 | B | Selectivity for mouse Kv1.3 over mouse Kv1.1 | Mus musculus | 1 | assay format | Scientific Literature |
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