# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3610737 | F | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in binucleated cells at 3.1 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 1.2 +/- 0.03 No_unit) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
2. | ALA3610748 | T | Toxicity in 2-Gy gamma irradiated human PBL assessed as cytokinesis-block proliferation index at 0.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs (Rvb = 1.6 +/- 0.1 No_unit) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA3610749 | T | Toxicity in 2-Gy gamma irradiated human PBL assessed as cytokinesis-block proliferation index at 1.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs (Rvb = 1.6 +/- 0.1 No_unit) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
4. | ALA3610750 | T | Toxicity in 2-Gy gamma irradiated human PBL assessed as cytokinesis-block proliferation index at 3.1 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs (Rvb = 1.6 +/- 0.1 No_unit) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
5. | ALA3610879 | F | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as binucleated cells with micronuclei at 0.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 15.5 +/- 0.6%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
6. | ALA3610880 | F | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as binucleated cells with micronuclei at 1.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 15.5 +/- 0.6%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
7. | ALA3610881 | F | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as binucleated cells with micronuclei at 3.1 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 15.5 +/- 0.6%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
8. | ALA3610892 | F | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in 1000 binucleated cells at 0.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 183 +/- 9.6 No_unit) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
9. | ALA3610893 | F | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in 1000 binucleated cells at 1.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 183 +/- 9.6 No_unit) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
10. | ALA3610894 | F | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in 1000 binucleated cells at 3.1 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 183 +/- 9.6 No_unit) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
11. | ALA3611004 | F | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as frequency of micronuclei at 1.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
12. | ALA3611005 | F | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as frequency of micronuclei at 3.1 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
13. | ALA3611740 | F | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in binucleated cells at 0.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 1.2 +/- 0.03 No_unit) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
14. | ALA3611741 | F | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in binucleated cells at 1.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 1.2 +/- 0.03 No_unit) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
15. | ALA3611752 | F | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as frequency of micronuclei at 0.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature |