| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3610737 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in binucleated cells at 3.1 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 1.2 +/- 0.03 No_unit) | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature | |
| 2. | ALA3610748 | Toxicity | Toxicity in 2-Gy gamma irradiated human PBL assessed as cytokinesis-block proliferation index at 0.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs (Rvb = 1.6 +/- 0.1 No_unit) | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature | |
| 3. | ALA3610749 | Toxicity | Toxicity in 2-Gy gamma irradiated human PBL assessed as cytokinesis-block proliferation index at 1.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs (Rvb = 1.6 +/- 0.1 No_unit) | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature | |
| 4. | ALA3610750 | Toxicity | Toxicity in 2-Gy gamma irradiated human PBL assessed as cytokinesis-block proliferation index at 3.1 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs (Rvb = 1.6 +/- 0.1 No_unit) | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature | |
| 5. | ALA3610879 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as binucleated cells with micronuclei at 0.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 15.5 +/- 0.6%) | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature | |
| 6. | ALA3610880 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as binucleated cells with micronuclei at 1.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 15.5 +/- 0.6%) | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature | |
| 7. | ALA3610881 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as binucleated cells with micronuclei at 3.1 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 15.5 +/- 0.6%) | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature | |
| 8. | ALA3610892 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in 1000 binucleated cells at 0.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 183 +/- 9.6 No_unit) | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature | |
| 9. | ALA3610893 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in 1000 binucleated cells at 1.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 183 +/- 9.6 No_unit) | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature | |
| 10. | ALA3610894 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in 1000 binucleated cells at 3.1 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 183 +/- 9.6 No_unit) | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature | |
| 11. | ALA3611004 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as frequency of micronuclei at 1.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay relative to control | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature | |
| 12. | ALA3611005 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as frequency of micronuclei at 3.1 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay relative to control | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature | |
| 13. | ALA3611740 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in binucleated cells at 0.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 1.2 +/- 0.03 No_unit) | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature | |
| 14. | ALA3611741 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in binucleated cells at 1.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 1.2 +/- 0.03 No_unit) | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature | |
| 15. | ALA3611752 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as frequency of micronuclei at 0.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay relative to control | Homo sapiens | 3 | ALA3608301 | cell-based format | Scientific Literature |
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