| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3610738 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in binucleated cells at 1.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 1.2 +/- 0.03 No_unit) | Homo sapiens | 2 | ALA3608301 | cell-based format | Scientific Literature | |
| 2. | ALA3610739 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in binucleated cells at 3.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 1.2 +/- 0.03 No_unit) | Homo sapiens | 1 | ALA3608301 | cell-based format | Scientific Literature | |
| 3. | ALA3610740 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in binucleated cells at 7 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 1.2 +/- 0.03 No_unit) | Homo sapiens | 1 | ALA3608301 | cell-based format | Scientific Literature | |
| 4. | ALA3610751 | Toxicity | Toxicity in 2-Gy gamma irradiated human PBL assessed as cytokinesis-block proliferation index at 1.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs (Rvb = 1.6 +/- 0.1 No_unit) | Homo sapiens | 2 | ALA3608301 | cell-based format | Scientific Literature | |
| 5. | ALA3610752 | Toxicity | Toxicity in 2-Gy gamma irradiated human PBL assessed as cytokinesis-block proliferation index at 3.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs (Rvb = 1.6 +/- 0.1 No_unit) | Homo sapiens | 1 | ALA3608301 | cell-based format | Scientific Literature | |
| 6. | ALA3610753 | Toxicity | Toxicity in 2-Gy gamma irradiated human PBL assessed as cytokinesis-block proliferation index at 7 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs (Rvb = 1.6 +/- 0.1 No_unit) | Homo sapiens | 1 | ALA3608301 | cell-based format | Scientific Literature | |
| 7. | ALA3610882 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as binucleated cells with micronuclei at 1.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 15.5 +/- 0.6%) | Homo sapiens | 2 | ALA3608301 | cell-based format | Scientific Literature | |
| 8. | ALA3610883 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as binucleated cells with micronuclei at 3.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 15.5 +/- 0.6%) | Homo sapiens | 1 | ALA3608301 | cell-based format | Scientific Literature | |
| 9. | ALA3610884 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as binucleated cells with micronuclei at 7 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 15.5 +/- 0.6%) | Homo sapiens | 1 | ALA3608301 | cell-based format | Scientific Literature | |
| 10. | ALA3611006 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as frequency of micronuclei at 1.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay relative to control | Homo sapiens | 2 | ALA3608301 | cell-based format | Scientific Literature | |
| 11. | ALA3611007 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as frequency of micronuclei at 3.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay relative to control | Homo sapiens | 1 | ALA3608301 | cell-based format | Scientific Literature | |
| 12. | ALA3611008 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as frequency of micronuclei at 7 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay relative to control | Homo sapiens | 1 | ALA3608301 | cell-based format | Scientific Literature | |
| 13. | ALA3611742 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in 1000 binucleated cells at 1.8 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 183 +/- 9.6 No_unit) | Homo sapiens | 2 | ALA3608301 | cell-based format | Scientific Literature | |
| 14. | ALA3611743 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in 1000 binucleated cells at 3.5 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 183 +/- 9.6 No_unit) | Homo sapiens | 1 | ALA3608301 | cell-based format | Scientific Literature | |
| 15. | ALA3611744 | Functional | Radioprotective activity in 2-Gy gamma irradiated human PBL assessed as incidence of micronuclei in 1000 binucleated cells at 7 uM treated for 2 to 19 hrs followed by compound washout measured after 72 hrs by cytochalasin-B-blocked micronucleus assay (Rvb = 183 +/- 9.6 No_unit) | Homo sapiens | 1 | ALA3608301 | cell-based format | Scientific Literature |
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