# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3615818 | Binding | Displacement of [3H]raclopride from dopamine D2 receptor in Sprague-Dawley rat striatal membranes after 30 mins | Rattus norvegicus | 11 | ALA3611999 | assay format | Scientific Literature | |
2. | ALA3615819 | Binding | Displacement of [3H]epibatidine from immunoimmobilized alpha4beta2 nAChR in Sprague-Dawley rat striatal membranes by liquid scintillation counting | Rattus norvegicus | 11 | ALA3611999 | assay format | Scientific Literature | |
3. | ALA3615820 | Binding | Displacement of [3H]epibatidine from immunoimmobilized alpha6beta2 nAChR in Sprague-Dawley rat striatal membranes by liquid scintillation counting | Rattus norvegicus | 11 | ALA3611999 | assay format | Scientific Literature | |
4. | ALA3615821 | Binding | Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampus membrane homogenates by gamma counting | Rattus norvegicus | 11 | ALA3611999 | assay format | Scientific Literature | |
5. | ALA3615826 | Binding | Antagonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of acetylcholine-induced inward current at holding potential of -70 mV by patch clamp technique | Homo sapiens | 8 | ALA3611999 | cell-based format | Scientific Literature | |
6. | ALA3615923 | Binding | Partial agonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as inward current at holding potential of -70 mV by patch clamp technique relative to acetylcholine | Homo sapiens | 8 | ALA3611999 | cell-based format | Scientific Literature | |
7. | ALA3615925 | Binding | Antagonist activity at nAChR in Sprague-Dawley rat striatal slices assessed as inhibition of nicotine-induced [3H]-dopamine release | Rattus norvegicus | 10 | ALA3611999 | assay format | Scientific Literature |