# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3616294 | B | Displacement of [3H]N6-R-phenylisopropyladenosine from human adenosine A1 receptor expressed in CHO cell membranes at 10 uM | Homo sapiens | 15 | ALA3612017 | cell-based format | Scientific Literature | |
2. | ALA3616296 | B | Displacement of [3H]2-[p-(2-carboxyethyl)phenyl-ethylamino]-5'-Nethylcarboxamidoadenosine from human adenosine A2A receptor expressed in HEK293 cell membranes at 10 uM | Homo sapiens | 18 | ALA3612017 | cell-based format | Scientific Literature | |
3. | ALA3616297 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adenosine A3 receptor expressed in CHO cell membranes | Homo sapiens | 18 | ALA3612017 | cell-based format | Scientific Literature | |
4. | ALA3616300 | B | Binding affinity to mouse adenosine A3 receptor expressed in HEK293 cell membranes | Mus musculus | 5 | ALA3612017 | cell-based format | Scientific Literature | |
5. | ALA3616301 | B | Binding affinity to canine adenosine A3 receptor expressed in HEK293 cell membranes | Canis lupus familiaris | 5 | ALA3612017 | cell-based format | Scientific Literature | |
6. | ALA3616304 | F | Analgesic activity in mouse chronic constriction injury model of neuropathic pain assessed as protection of ipsilateral hind paw mechanoallodynia of sciatic nerve at 0.3 to 30 umol/kg administered through oral gavage at point of peak pain on day 7 relative to control measured at 1 hr | Mus musculus | 11 | ALA3612017 | organism-based format | Scientific Literature | |
7. | ALA3616305 | F | Analgesic activity in mouse chronic constriction injury model of neuropathic pain assessed as protection of ipsilateral hind paw mechanoallodynia of sciatic nerve at 0.3 to 30 umol/kg administered through oral gavage at point of peak pain on day 7 measured at 3 hrs | Mus musculus | 11 | ALA3612017 | organism-based format | Scientific Literature | |
8. | ALA3616306 | F | Analgesic activity in mouse chronic constriction injury model of neuropathic pain assessed as time of peak protection at 0.3 to 30 umol/kg administered through oral gavage at point of peak pain on day 7 | Mus musculus | 11 | ALA3612017 | organism-based format | Scientific Literature | |
9. | ALA3616307 | F | Analgesic activity in mouse chronic constriction injury model of neuropathic pain assessed as protection of ipsilateral hind paw mechanoallodynia of sciatic nerve at 0.3 to 30 umol/kg administered through oral gavage at point of peak pain on day 7 | Mus musculus | 2 | ALA3612017 | organism-based format | Scientific Literature | |
10. | ALA3616311 | A | Effect on contralateral side hind paw in mouse chronic constriction injury model of neuropathic pain at 0.3 to 30 umol/kg administered through oral gavage at point of peak pain on day 7 | Mus musculus | 11 | ALA3612017 | organism-based format | Scientific Literature | |
11. | ALA4731036 | A | Stability in Sprague-Dawley rat plasma | Rattus norvegicus | 5 | ALA4725439 | cell-free format | Scientific Literature | |
12. | ALA4731037 | A | Stability in Sprague-Dawley rat liver microsomes | Rattus norvegicus | 5 | ALA4725439 | microsome format | Scientific Literature | |
13. | ALA4731038 | A | Cytotoxicity against human HepG2 cells | Homo sapiens | 5 | ALA4725439 | cell-based format | Scientific Literature | |
14. | ALA4731039 | A | Oral bioavailability in Sprague-Dawley rat | Rattus norvegicus | 5 | ALA4725439 | organism-based format | Scientific Literature |