# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3616294 | B | Displacement of [3H]N6-R-phenylisopropyladenosine from human adenosine A1 receptor expressed in CHO cell membranes at 10 uM | Homo sapiens | 15 | ALA3612017 | cell-based format | Scientific Literature | |
2. | ALA3616296 | B | Displacement of [3H]2-[p-(2-carboxyethyl)phenyl-ethylamino]-5'-Nethylcarboxamidoadenosine from human adenosine A2A receptor expressed in HEK293 cell membranes at 10 uM | Homo sapiens | 18 | ALA3612017 | cell-based format | Scientific Literature | |
3. | ALA3616297 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adenosine A3 receptor expressed in CHO cell membranes | Homo sapiens | 18 | ALA3612017 | cell-based format | Scientific Literature | |
4. | ALA3616298 | B | Displacement of [3H]MRS1754 from human adenosine A2B receptor expressed in HEK293 cell membranes at 10 uM | Homo sapiens | 2 | ALA3612017 | cell-based format | Scientific Literature | |
5. | ALA3616300 | B | Binding affinity to mouse adenosine A3 receptor expressed in HEK293 cell membranes | Mus musculus | 5 | ALA3612017 | cell-based format | Scientific Literature | |
6. | ALA3616301 | B | Binding affinity to canine adenosine A3 receptor expressed in HEK293 cell membranes | Canis lupus familiaris | 5 | ALA3612017 | cell-based format | Scientific Literature | |
7. | ALA3616302 | B | Binding affinity to 5HT2B receptor (unknown origin) | Homo sapiens | 2 | ALA3612017 | single protein format | Scientific Literature | |
8. | ALA3616304 | F | Analgesic activity in mouse chronic constriction injury model of neuropathic pain assessed as protection of ipsilateral hind paw mechanoallodynia of sciatic nerve at 0.3 to 30 umol/kg administered through oral gavage at point of peak pain on day 7 relative to control measured at 1 hr | Mus musculus | 11 | ALA3612017 | organism-based format | Scientific Literature | |
9. | ALA3616305 | F | Analgesic activity in mouse chronic constriction injury model of neuropathic pain assessed as protection of ipsilateral hind paw mechanoallodynia of sciatic nerve at 0.3 to 30 umol/kg administered through oral gavage at point of peak pain on day 7 measured at 3 hrs | Mus musculus | 11 | ALA3612017 | organism-based format | Scientific Literature | |
10. | ALA3616306 | F | Analgesic activity in mouse chronic constriction injury model of neuropathic pain assessed as time of peak protection at 0.3 to 30 umol/kg administered through oral gavage at point of peak pain on day 7 | Mus musculus | 11 | ALA3612017 | organism-based format | Scientific Literature | |
11. | ALA3616311 | A | Effect on contralateral side hind paw in mouse chronic constriction injury model of neuropathic pain at 0.3 to 30 umol/kg administered through oral gavage at point of peak pain on day 7 | Mus musculus | 11 | ALA3612017 | organism-based format | Scientific Literature | |
12. | ALA4011340 | B | Enhancing of [125I]RTI-55 binding to recombinant human DAT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | ALA4007505 | cell-based format | Scientific Literature | |
13. | ALA4011341 | B | Enhancing of [3H]mazindol binding to recombinant human DAT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | ALA4007505 | cell-based format | Scientific Literature | |
14. | ALA4011342 | B | Enhancing of [125I]RTI-55 binding to recombinant human NET expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | ALA4007505 | cell-based format | Scientific Literature | |
15. | ALA4011343 | B | Inhibition of recombinant human DAT expressed in HEK293 cell membranes assessed as reduction in [3H]-DA uptake incubated for 22 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | ALA4007505 | cell-based format | Scientific Literature | |
16. | ALA4011344 | B | Enhancing of [3H]mazindol binding to recombinant human NET expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 12 | ALA4007505 | cell-based format | Scientific Literature | |
17. | ALA4011345 | B | Inhibition of recombinant human NET expressed in HEK293 cell membranes assessed as reduction in [3H]-norepinephrine uptake incubated for 22 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | ALA4007505 | cell-based format | Scientific Literature | |
18. | ALA4011346 | B | Enhancing of [125I]RTI-55 binding to recombinant human SERT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | ALA4007505 | cell-based format | Scientific Literature | |
19. | ALA4011347 | B | Enhancing of [3H]mazindol binding to recombinant human SERT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 10 | ALA4007505 | cell-based format | Scientific Literature | |
20. | ALA4011348 | B | Inhibition of recombinant human SERT expressed in HEK293 cell membranes assessed as reduction in [3H]5-HT uptake incubated for 22 mins by micro beta scintillation counting analysis | Homo sapiens | 13 | ALA4007505 | cell-based format | Scientific Literature |