| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3616266 | Binding | Inhibition of APOBEC3A (unknown origin) by fluorescence-based ssDNA C-to-U deaminase assay | Homo sapiens | 1 | ALA3612064 | single protein format | Scientific Literature | |
| 2. | ALA3616267 | Binding | Inhibition of APOBEC3G (unknown origin) fluorescence-based ssDNA C-to-U deaminase assay | Homo sapiens | 1 | ALA3612064 | single protein format | Scientific Literature | |
| 3. | ALA3616268 | Toxicity | Toxicity against HEK293T cells assessed as cell viability at 50 uM incubated for 5 days | Homo sapiens | 1 | ALA3612064 | cell-based format | Scientific Literature | |
| 4. | ALA3616269 | Toxicity | Toxicity against HeLa cells assessed as cell viability at 50 uM incubated for 5 days | Homo sapiens | 1 | ALA3612064 | cell-based format | Scientific Literature | |
| 5. | ALA3616270 | Binding | Inhibition of APOBEC3G (unknown origin) up to 200 uM using ssDNA oligomer 5'-6-FAM-AAA-TAT-TCC-CTA-ATA-GAT-AAT-GTG-A-TAMRA-3' by fluorescence-based deamination assay | Homo sapiens | 1 | ALA3612064 | single protein format | Scientific Literature | |
| 6. | ALA3616271 | Binding | Inhibition of APOBEC3G (unknown origin) up to 200 uM incubated for 3 to 72 days using ssDNA oligomer 5'-6-FAM-AAA-TAT-TCC-CTA-ATA-GAT-AAT-GTG-A-TAMRA-3' by fluorescence-based deamination assay | Homo sapiens | 1 | ALA3612064 | single protein format | Scientific Literature | |
| 7. | ALA3616272 | Binding | Inhibition of APOBEC3G (unknown origin) assessed as remaining enzyme activity at 200 uM incubated for 3 days using ssDNA oligomer 5'-6-FAM-AAA-TAT-TCC-CTA-ATA-GAT-AAT-GTG-A-TAMRA-3' by fluorescence-based deamination assay | Homo sapiens | 1 | ALA3612064 | single protein format | Scientific Literature | |
| 8. | ALA3616273 | Binding | Inhibition of APOBEC3G (unknown origin) assessed as remaining enzyme activity at 200 uM incubated for 21 days using ssDNA oligomer 5'-6-FAM-AAA-TAT-TCC-CTA-ATA-GAT-AAT-GTG-A-TAMRA-3' by fluorescence-based deamination assay | Homo sapiens | 1 | ALA3612064 | single protein format | Scientific Literature | |
| 9. | ALA3616274 | Binding | Inhibition of APOBEC3G (unknown origin) assessed as remaining enzyme activity at 200 uM incubated for 38 days using ssDNA oligomer 5'-6-FAM-AAA-TAT-TCC-CTA-ATA-GAT-AAT-GTG-A-TAMRA-3' by fluorescence-based deamination assay | Homo sapiens | 1 | ALA3612064 | single protein format | Scientific Literature | |
| 10. | ALA3616275 | Binding | Inhibition of APOBEC3G (unknown origin) assessed as remaining enzyme activity at 200 uM incubated for 74 days using ssDNA oligomer 5'-6-FAM-AAA-TAT-TCC-CTA-ATA-GAT-AAT-GTG-A-TAMRA-3' by fluorescence-based deamination assay | Homo sapiens | 1 | ALA3612064 | single protein format | Scientific Literature | |
| 11. | ALA3616276 | Physicochemical | Drug metabolism assessed as compound-5 formation in DMSO incubated for 16 months by 1H and 13C NMR method | 1 | ALA3612064 | small-molecule physicochemical format | Scientific Literature | ||
| 12. | ALA3616277 | Physicochemical | Drug metabolism assessed as compound-5 formation in DMSO incubated for 16 months by IR method | 1 | ALA3612064 | small-molecule physicochemical format | Scientific Literature | ||
| 13. | ALA3616278 | Physicochemical | Drug metabolism assessed as compound-5 formation in DMSO incubated for 16 months by LC-MS method | 1 | ALA3612064 | small-molecule physicochemical format | Scientific Literature | ||
| 14. | ALA3614122 | Physicochemical | Drug metabolism assessed as compound decompostion after irradiation with visible light under oxygen-saturated environment in presence of rose bengal photosensitizer by LC/MS method | 1 | ALA3612064 | small-molecule physicochemical format | Scientific Literature | ||
| 15. | ALA3614124 | Physicochemical | Drug metabolism assessed as oxidative compound decompostion after irradiation with visible light under oxygen-saturated environment in absence of rose bengal photosensitizer by LC/MS method | 1 | ALA3612064 | small-molecule physicochemical format | Scientific Literature | ||
| 16. | ALA3614126 | Physicochemical | Drug metabolism assessed as oxidative compound decompostion after irradiation with visible light under N2 environment in presence of rose bengal photosensitizer incubated for 9 hrs by LC/MS method | 1 | ALA3612064 | small-molecule physicochemical format | Scientific Literature | ||
| 17. | ALA3614127 | Physicochemical | Drug metabolism assessed as oxidative compound decompostion after irradiation with visible light under oxygen-saturated environment using [18]O2 in presence of rose bengal photosensitizer using by LC/MS method | 1 | ALA3612064 | small-molecule physicochemical format | Scientific Literature | ||
| 18. | ALA3614128 | Physicochemical | Stability in DMSO solution assessed as parent compound remaining at 10 mM incubated for 38 days exposed to laboratory air by LC/MS method | 22 | ALA3612064 | small-molecule physicochemical format | Scientific Literature | ||
| 19. | ALA3614129 | Physicochemical | Drug metabolism in DMSO solution assessed as compound decomposition by measuring lactam level at 10 mM incubated for 38 days exposed to laboratory air by LC/MS method | 22 | ALA3612064 | small-molecule physicochemical format | Scientific Literature | ||
| 20. | ALA3614130 | Physicochemical | Drug metabolism in DMSO solution assessed as compound decomposition by measuring carboxylic acid level at 10 mM incubated for 38 days exposed to laboratory air by LC/MS method | 22 | ALA3612064 | small-molecule physicochemical format | Scientific Literature |
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