# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3616153 | B | Inhibition of human DGAT1 expressed in human Hep3B cells incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and luminometry based flash plate assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
2. | ALA3616154 | B | Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and luminometry based flash plate assay | Mus musculus | 24 | single protein format | Scientific Literature | ||
3. | ALA3616155 | F | Reduction in plasma TG levels in C57BL/6 mouse at 3 mg/kg, po dosed 30 mins before corn oil dosing and measured 2 hrs post lipid challenge by colometry based oral lipid tolerance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
4. | ALA3616156 | F | Reduction in plasma TG levels in TallyHo mouse at 3 mg/kg, po dosed 30 mins before corn oil dosing and measured 2 hrs post lipid challenge by colometry based oral lipid tolerance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
5. | ALA3616157 | F | Reduction in plasma TG levels in TallyHo mouse at 0.5 mg/kg, po dosed 30 mins before corn oil dosing and measured 2 hrs post lipid challenge by colometry based oral lipid tolerance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
6. | ALA3616158 | F | Reduction in plasma TG levels in TallyHo mouse at 1 mg/kg, po dosed 30 mins before corn oil dosing and measured 2 hrs post lipid challenge by colometry based oral lipid tolerance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
7. | ALA3616159 | F | Reduction in plasma TG levels in TallyHo mouse at 10 mg/kg, po dosed 30 mins before corn oil dosing and measured 2 hrs post lipid challenge by colometry based oral lipid tolerance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA3616160 | F | Reduction in plasma TG levels in TallyHo mouse at 0.5 to 10 mg/kg, po dosed 30 mins before corn oil dosing and measured 2 hrs post lipid challenge by colometry based oral lipid tolerance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
9. | ALA3616161 | F | Reduction in lipid deposits in Zebrafish at 10 uM incubated for 3 days by LipidGreen2 due based fluorescence stereomicroscopy | Danio rerio | 1 | organism-based format | Scientific Literature | ||
10. | ALA3616162 | F | Reduction in body weight gain in high fat diet fed diet-induced obesity mouse at 10 mg/kg, po administered daily for 4 weeks | Mus musculus | 1 | organism-based format | Scientific Literature | ||
11. | ALA3616163 | A | Effect on food intake in high fat diet fed diet-induced obesity mouse at 10 mg/kg, po administered daily for 4 weeks | Mus musculus | 1 | organism-based format | Scientific Literature | ||
12. | ALA3616164 | F | Reduction in glucose AUC in high fat diet fed diet-induced obesity mouse at 10 mg/kg, po administered daily for 4 weeks by oral glucose tolerance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
13. | ALA3616165 | B | Inhibition of human DGAT2 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA3616166 | A | Stability in human liver microsomes assessed as parent compound remaining after 30 mins | Homo sapiens | 1 | assay format | Scientific Literature | ||
15. | ALA3616167 | A | Stability in rat liver microsomes assessed as parent compound remaining after 30 mins | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
16. | ALA3616168 | A | Inhibition of CYP1A2 (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
17. | ALA3616169 | A | Inhibition of CYP2C19 (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA3616170 | A | Inhibition of CYP3A4 (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA3616171 | A | Inhibition of CYP2C9 (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA3616172 | A | Inhibition of CYP2D6 (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature |