| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3614582 | B | Inhibition of recombinant human DAAO expressed in HEK cells using D-serine as substrate assessed as formation of alpha-keto acid, ammonia, hydrogen peroxidase after 20 mins by horseradish peroxidase/o-phenylenediamine-based assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 2. | ALA3614583 | B | Competitive inhibition of recombinant human DAAO expressed in HEK cells by double reciprocal plot analysis in presence of D-serine | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA3614584 | B | Inhibition of recombinant human DAAO expressed in HEK cells in presence of 10 to 100 uM of FAD | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA3614585 | T | Mutagenicity in Salmonella typhimurium TA100 by Ames test in presence of S9 mixture | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA3614586 | A | Metabolic stability in mouse liver microsomes assessed as compound remaining at 5 uM after 60 mins by LC/MS/MS analysis in presence of UDPGA | Mus musculus | 6 | assay format | Scientific Literature | ||
| 6. | ALA3614587 | A | Metabolic stability in mouse liver microsomes assessed as compound remaining at 5 uM after 60 mins by LC/MS/MS analysis in presence of NADPH | Mus musculus | 6 | assay format | Scientific Literature | ||
| 7. | ALA3614588 | B | Inhibition of human ERG up to 25 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3614589 | B | Inhibition of NMDA receptor agonist binding site (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 9. | ALA3614590 | B | Inhibition of NMDA receptor glycine binding site (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 10. | ALA3614591 | B | Inhibition of NMDA receptor phencyclidine binding site (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 11. | ALA3614592 | B | Inhibition of NMDA receptor MK801 binding site (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 12. | ALA3614593 | B | Inhibition of strychnine-sensitive glycine receptor (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA3614594 | B | Inhibition of MAO-A (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA3614595 | B | Inhibition of MAO-B (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA3614701 | A | Tmax in CD1 mouse at 30 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA3614702 | A | Cmax in CD1 mouse at 30 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA3614703 | A | AUClast in CD1 mouse at 30 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA3614704 | A | Oral bioavailability in CD1 mouse at 30 mg/kg | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 19. | ALA3614705 | A | Clearance in CD1 mouse at 30 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA3614706 | A | Volume of distribution in CD1 mouse at 30 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature |
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