#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3618962	Binding	Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by fluorescent assay	Homo sapiens	41	ALA3616381	assay format	Scientific Literature
2.	ALA3618963	Physicochemical	Chromatographic hydrophobicity index, log D of the compound at pH 7.4		41	ALA3616381	small-molecule physicochemical format	Scientific Literature
3.	ALA3618964	Physicochemical	Kinetic solubility of the compound by chemi-luminescent nitrogen detection method		41	ALA3616381	small-molecule physicochemical format	Scientific Literature
4.	ALA3618965	Binding	Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysis	Homo sapiens	38	ALA3616381	assay format	Scientific Literature
5.	ALA3618972	Binding	Inhibition of BCATc (unknown origin)	Homo sapiens	2	ALA3616381	single protein format	Scientific Literature
6.	ALA3618975	ADME	Ratio of drug level in brain to blood in C57-B6 mouse at 10 mg/kg, po	Mus musculus	2	ALA3616381	organism-based format	Scientific Literature
7.	ALA3618976	ADME	AUC (0 to t) in C57-B6 mouse at 1 mg/kg, iv and 5 mg/kg, po	Mus musculus	2	ALA3616381	organism-based format	Scientific Literature
8.	ALA3618977	ADME	Half life in C57-B6 mouse at 1 mg/kg, iv and 5 mg/kg, po	Mus musculus	2	ALA3616381	organism-based format	Scientific Literature
9.	ALA3618978	ADME	Blood clearance in C57-B6 mouse at 1 mg/kg, iv and 5 mg/kg, po	Mus musculus	2	ALA3616381	organism-based format	Scientific Literature
10.	ALA3618979	ADME	Oral bioavailability in C57-B6 mouse at 5 mg/kg	Mus musculus	3	ALA3616381	organism-based format	Scientific Literature
11.	ALA3618980	ADME	Protein binding in plasma (unknown origin)	Not specified	2	ALA3616381	cell-free format	Scientific Literature
12.	ALA3618981	Functional	Inhibition of BCATm in C57Black/6J mouse assessed as increase of leucine level in serum at 10 to 100 mg/kg, po administered 5 hrs before amino acid meal by HPLC analysis	Mus musculus	1	ALA3616381	organism-based format	Scientific Literature
13.	ALA3618983	Functional	Inhibition of BCATm in C57Black/6J mouse assessed as increase of isoleucine level in serum at 10 to 100 mg/kg, po administered 5 hrs before amino acid meal by HPLC analysis	Mus musculus	1	ALA3616381	organism-based format	Scientific Literature
14.	ALA3618985	Functional	Inhibition of BCATm in C57Black/6J mouse assessed as increase of valine level in serum at 10 to 100 mg/kg, po administered 5 hrs before amino acid meal by HPLC analysis	Mus musculus	1	ALA3616381	organism-based format	Scientific Literature
15.	ALA3618987	ADME	Inhibition of BCATm in C57Black/6J mouse assessed as increase of serine level in serum at 10 to 100 mg/kg, po administered 5 hrs before amino acid meal by HPLC analysis	Mus musculus	1	ALA3616381	organism-based format	Scientific Literature
16.	ALA3619126	ADME	Inhibition of BCATm in C57Black/6J mouse assessed as increase of tyrosine level in serum at 10 to 100 mg/kg, po administered 5 hrs before amino acid meal by HPLC analysis	Mus musculus	1	ALA3616381	organism-based format	Scientific Literature
17.	ALA3619128	Functional	Inhibition of BCATm in po dosed C57Black/6J mouse assessed as increase of leucine level in serum administered 5 hrs before amino acid meal by HPLC analysis	Mus musculus	1	ALA3616381	organism-based format	Scientific Literature
18.	ALA3619635	Functional	Inhibition of BCATm in po dosed C57Black/6J mouse assessed as increase of isoleucine level in serum administered 5 hrs before amino acid meal by HPLC analysis	Mus musculus	1	ALA3616381	organism-based format	Scientific Literature
19.	ALA3619636	Functional	Inhibition of BCATm in po dosed C57Black/6J mouse assessed as increase of valine level in serum administered 5 hrs before amino acid meal by HPLC analysis	Mus musculus	1	ALA3616381	organism-based format	Scientific Literature
20.	ALA3619637	Functional	Inhibition of BCATm in C57Black/6J mouse assessed as increase of leucine level in serum at 100 mg/kg, po administered 5 hrs before amino acid meal by HPLC analysis (Rvb = 473 uM)	Mus musculus	1	ALA3616381	organism-based format	Scientific Literature