# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3619474 | B | Induction of Tubulin depolymerization in human MCF7 cells by immunofluorescence analysis | Homo sapiens | 3 | ALA3616442 | cell-based format | Scientific Literature | |
2. | ALA4384039 | F | Cell cycle arrest in human HL60 cells assessed as accumulation of cells at G2/M phase at 10 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 13 | ALA4382230 | cell-based format | Scientific Literature | |
3. | ALA4384040 | B | Inhibition of tubulin (unknown origin) polymerization at 27.5 uM measured over 70 mins by turbidity method | Homo sapiens | 10 | ALA4382230 | protein complex format | Scientific Literature | |
4. | ALA4384041 | B | Binding affinity to tubulin (unknown origin) by UV-vis spectroscopic analysis | Homo sapiens | 10 | ALA4382230 | protein complex format | Scientific Literature | |
5. | ALA4384042 | P | Apparent solubility of compound in sodium phosphate buffer at 15 uM after 20 mins | 10 | ALA4382230 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4384043 | F | Cytotoxicity against human A2780 cells after 48 hrs by MTT assay | Homo sapiens | 13 | ALA4382230 | cell-based format | Scientific Literature | |
7. | ALA4384044 | F | Cytotoxicity against human A2780AD cells after 48 hrs by MTT assay | Homo sapiens | 13 | ALA4382230 | cell-based format | Scientific Literature | |
8. | ALA4384045 | F | Ratio of IC50 for human A2780AD cells to IC50 for human A2780 cells | Homo sapiens | 13 | ALA4382230 | assay format | Scientific Literature | |
9. | ALA4384046 | A | Cytotoxicity against mouse NIH/3T3 cells after 48 hrs by MTT assay | Mus musculus | 13 | ALA4382230 | cell-based format | Scientific Literature | |
10. | ALA4384047 | F | Cytotoxicity against mouse NIH/3T3 cells harboring MDR G185 after 48 hrs by MTT assay | Mus musculus | 13 | ALA4382230 | cell-based format | Scientific Literature | |
11. | ALA4384048 | U | Ratio of IC50 for mouse NIH/3T3 cells harboring MDR G185 to IC50 for mouse NIH/3T3 cells | Mus musculus | 13 | ALA4382230 | assay format | Scientific Literature | |
12. | ALA4384049 | F | Cytotoxicity against human A549 cells assessed as reduction in cell survival at 0.1 to 10 uM after 18 hrs by MTT assay | Homo sapiens | 4 | ALA4382230 | cell-based format | Scientific Literature | |
13. | ALA4384050 | F | Cytotoxicity against mouse B16F10 cells assessed as reduction in cell survival at 0.1 to 10 uM after 18 hrs by MTT assay | Mus musculus | 4 | ALA4382230 | cell-based format | Scientific Literature | |
14. | ALA4384051 | F | Cytotoxicity against human PC9 cells assessed as reduction in cell survival at 0.1 to 10 uM after 18 hrs by MTT assay | Homo sapiens | 4 | ALA4382230 | cell-based format | Scientific Literature | |
15. | ALA4384052 | F | Cytotoxicity against human HCC827 cells assessed as reduction in cell survival at 0.1 to 10 uM after 18 hrs by MTT assay | Homo sapiens | 4 | ALA4382230 | cell-based format | Scientific Literature | |
16. | ALA4384053 | F | Cytotoxicity against human HCC827 cells assessed as reduction in cell survival at 0.1 to 10 uM after 50 to 60 hrs by MTT assay | Homo sapiens | 4 | ALA4382230 | cell-based format | Scientific Literature | |
17. | ALA4384054 | F | Induction of apoptosis in human PC9 cells assessed as increase in caspase-3 expression at 10 uM after 18 hrs by Western blot analysis | Homo sapiens | 2 | ALA4382230 | cell-based format | Scientific Literature | |
18. | ALA4384055 | F | Induction of apoptosis in human PC9 cells assessed as increase in p21 expression at 10 uM after 18 hrs by Western blot analysis | Homo sapiens | 2 | ALA4382230 | cell-based format | Scientific Literature | |
19. | ALA4384056 | F | Induction of apoptosis in human PC9 cells assessed as reduction in cyclin D1 expression at 10 uM after 18 hrs by Western blot analysis | Homo sapiens | 2 | ALA4382230 | cell-based format | Scientific Literature | |
20. | ALA4384057 | F | Induction of apoptosis in human HCC827 cells assessed as increase in caspase-3 expression at 10 uM after 18 hrs by Western blot analysis | Homo sapiens | 2 | ALA4382230 | cell-based format | Scientific Literature |