| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3619484 | B | Inhibition of ERCC1-XPF (unknown origin) by high-throughput fluorescence based in-vitro endonuclease assay | Homo sapiens | 38 | ALA3616448 | protein complex format | Scientific Literature | |
| 2. | ALA3619485 | B | Inhibition of FEN1 (unknown origin) | Homo sapiens | 38 | ALA3616448 | single protein format | Scientific Literature | |
| 3. | ALA3619486 | B | Inhibition of DNAse1 (unknown origin) | Homo sapiens | 30 | ALA3616448 | single protein format | Scientific Literature | |
| 4. | ALA3619487 | B | Binding affinity to ERCC1-XPF (unknown origin) by SPR assay | Homo sapiens | 1 | ALA3616448 | protein complex format | Scientific Literature | |
| 5. | ALA3619488 | B | Binding affinity to ERCC1-XPF (unknown origin) assessed as melting temperature by thermal shift assay | Homo sapiens | 1 | ALA3616448 | protein complex format | Scientific Literature | |
| 6. | ALA3619489 | B | Inhibition of ERCC1-XPF in human A375 cells assessed as reduction in direct nucleotide excision repair of UV-damaged pEGFP plasmid up to 10 uM incubated for 24 hrs by recombinant GFP reporter assay | Homo sapiens | 1 | ALA3616448 | cell-based format | Scientific Literature | |
| 7. | ALA3619490 | B | Inhibition of ERCC1-XPF in human A375 cells assessed as potentiation of cisplatin-induced cytotoxicity at 0.1 to 3 uM incubated for 5 days | Homo sapiens | 1 | ALA3616448 | cell-based format | Scientific Literature | |
| 8. | ALA3619491 | A | Cytotoxicity against human A375 cells assessed as reduction in cell number at 0.1 to 3 uM incubated for 5 days | Homo sapiens | 1 | ALA3616448 | cell-based format | Scientific Literature | |
| 9. | ALA3619492 | B | Inhibition of ERCC1-XPF in human A375 cells assessed as induction of delay in DNA repair by measuring cumulative frequency of cells up to 10 uM pre-incubated for 1 hr before cisplatin exposure for 1 hr by immunohistochemistry based gammaH2AX foci assay | Homo sapiens | 1 | ALA3616448 | cell-based format | Scientific Literature | |
| 10. | ALA3619493 | P | Lipophilicity, log D of the compound | 3 | ALA3616448 | small-molecule physicochemical format | Scientific Literature | ||
| 11. | ALA3619494 | A | Cytotoxicity against human HepG2 cells | Homo sapiens | 3 | ALA3616448 | cell-based format | Scientific Literature | |
| 12. | ALA3619495 | A | Half life in mouse liver microsomes | Mus musculus | 3 | ALA3616448 | assay format | Scientific Literature | |
| 13. | ALA3619496 | A | Half life in human liver microsomes | Homo sapiens | 3 | ALA3616448 | assay format | Scientific Literature | |
| 14. | ALA3619497 | P | Apparent permeability by PAMPA method | 3 | ALA3616448 | small-molecule physicochemical format | Scientific Literature |
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