# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3619967 | B | Inhibition of kelch domain of Keap1 (unknown origin) interaction to high affinity ETGE motif from Nrf2 unknown origin) at 100 uM by fluorescence polarization assay | Homo sapiens | 58 | ALA3616400 | protein format | Scientific Literature | |
2. | ALA3619968 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as induction of NQO1 production at 10 uM after 24 hrs by MTT colorimetric assay relative to control | Mus musculus | 61 | ALA3616400 | cell-based format | Scientific Literature | |
3. | ALA3620075 | B | Inhibition of kelch domain of Keap1 (unknown origin) interaction to high affinity ETGE motif from Nrf2 by fluorescence polarization assay | Homo sapiens | 14 | ALA3616400 | protein format | Scientific Literature | |
4. | ALA3620076 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as concentration required to 2 fold induction of NQO1 production after 24 hrs by MTT colorimetric assay | Mus musculus | 11 | ALA3616400 | cell-based format | Scientific Literature | |
5. | ALA3620078 | F | Increase of Nrf2 protein level in mouse Hepa1c1c7 cells at 10 uM after 24 hrs by Western blot analysis | Mus musculus | 4 | ALA3616400 | cell-based format | Scientific Literature | |
6. | ALA3620080 | F | Increase of Nrf2 protein level in mouse Hepa1c1c7 cells at 10 uM by Western blot analysis | Mus musculus | 3 | ALA3616400 | cell-based format | Scientific Literature | |
7. | ALA3620083 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as increase of HO-1 expression at 10 uM after 6 hrs by Western blot analysis | Mus musculus | 3 | ALA3616400 | cell-based format | Scientific Literature | |
8. | ALA3620084 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as increase of NQO1 expression at 10 uM measured before 24 hrs by Western blot analysis | Mus musculus | 3 | ALA3616400 | cell-based format | Scientific Literature |