# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3618837 | F | Photocytotoxicity against human Jurkat cells assessed as growth inhibition at 2.5 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
2. | ALA3618838 | F | Photocytotoxicity against human Jurkat cells assessed as growth inhibition at 1.25 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
3. | ALA3618988 | F | Photocytotoxicity against human HL60 cells assessed as growth inhibition at 2.5 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
4. | ALA3618989 | F | Photocytotoxicity against human HL60 cells assessed as growth inhibition at 1.25 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
5. | ALA3618990 | F | Photocytotoxicity against human MCF7 cells assessed as growth inhibition at 3.75 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
6. | ALA3618991 | F | Photocytotoxicity against human MCF7 cells assessed as growth inhibition at 2.5 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
7. | ALA3618992 | F | Photocytotoxicity against human A549 cells assessed as growth inhibition at 3.75 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
8. | ALA3618993 | F | Photocytotoxicity against human A549 cells assessed as growth inhibition at 2.5 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
9. | ALA3618994 | F | Photocytotoxicity against human LoVo cells assessed as growth inhibition at 3.75 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
10. | ALA3618995 | F | Photocytotoxicity against human LoVo cells assessed as growth inhibition at 2.5 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
11. | ALA3618996 | F | Photocytotoxicity against human A549 cells assessed as inhibition of colony formation at 2.5 J/cm'2 irradiation after 1 to 2 weeks using crystal violet staining by optical microscopy | Homo sapiens | 4 | ALA3616466 | cell-based format | Scientific Literature | |
12. | ALA3619000 | F | Induction of apoptosis in human Jurkat cells assessed as reduction in alive cells using Annexin-V and propidium iodide staining at 1 to 2 uM measured 24 hrs post 2.5 J/cm'2 irradiation by flow cytometry analysis | Homo sapiens | 4 | ALA3616466 | cell-based format | Scientific Literature | |
13. | ALA3619001 | F | Induction of apoptosis in human Jurkat cells assessed as increase in cleaved caspase 3 level at 1 uM measured 24 hrs post 2.5 J/cm'2 irradiation by Western blot analysis | Homo sapiens | 4 | ALA3616466 | cell-based format | Scientific Literature | |
14. | ALA3619002 | F | Induction of apoptosis in human Jurkat cells assessed as reduction in mitochondrial potential at 1 to 2 uM using JC-1 staining measured 24 hrs post 2.5 J/cm'2 irradiation by FACS assay | Homo sapiens | 4 | ALA3616466 | cell-based format | Scientific Literature | |
15. | ALA3619003 | F | Induction of apoptosis in human Jurkat cells assessed as ROS production at 1 to 2 uM using HE and DCFDA staining measured 24 hrs post 2.5 J/cm'2 irradiation by FACS assay | Homo sapiens | 4 | ALA3616466 | cell-based format | Scientific Literature | |
16. | ALA3619004 | F | Induction of apoptosis in human Jurkat cells assessed as lysosome death at 1 to 2 uM using acridine orange staining measured 24 hrs post 2.5 J/cm'2 irradiation by flow cytometry | Homo sapiens | 4 | ALA3616466 | cell-based format | Scientific Literature | |
17. | ALA3619005 | B | Induction of DNA damage in Escherichia coli pBR322 DNA measured at 7.5 J/cm'2 UV-A irradiation by neutral agarose electrophoresis | Escherichia coli | 4 | ALA3616466 | assay format | Scientific Literature | |
18. | ALA3619006 | B | Protein photodamage in bovine serum albumin assessed as reduction in tryptophan fluorescence at 10 uM measured after irradiation by fluorimetry | Bos taurus | 3 | ALA3616466 | single protein format | Scientific Literature | |
19. | ALA3619007 | B | Induction of oxidative damage in bovine serum albumin assessed as increase in carbonyl formation rate at 10 uM measured after irradiation by spectrophotometer | Bos taurus | 4 | ALA3616466 | single protein format | Scientific Literature | |
20. | ALA3619008 | B | Protein photodamage in RNAse A (unknown origin) assessed as reduction in tyrosine fluorescence at 10 uM measured after irradiation by fluorimetry | Homo sapiens | 4 | ALA3616466 | single protein format | Scientific Literature |