# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3618837 | F | Photocytotoxicity against human Jurkat cells assessed as growth inhibition at 2.5 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
2. | ALA3618838 | F | Photocytotoxicity against human Jurkat cells assessed as growth inhibition at 1.25 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
3. | ALA3618988 | F | Photocytotoxicity against human HL60 cells assessed as growth inhibition at 2.5 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
4. | ALA3618989 | F | Photocytotoxicity against human HL60 cells assessed as growth inhibition at 1.25 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
5. | ALA3618990 | F | Photocytotoxicity against human MCF7 cells assessed as growth inhibition at 3.75 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
6. | ALA3618991 | F | Photocytotoxicity against human MCF7 cells assessed as growth inhibition at 2.5 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
7. | ALA3618992 | F | Photocytotoxicity against human A549 cells assessed as growth inhibition at 3.75 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
8. | ALA3618993 | F | Photocytotoxicity against human A549 cells assessed as growth inhibition at 2.5 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
9. | ALA3618994 | F | Photocytotoxicity against human LoVo cells assessed as growth inhibition at 3.75 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
10. | ALA3618995 | F | Photocytotoxicity against human LoVo cells assessed as growth inhibition at 2.5 J/cm'2 irradiation for 30 mins followed by drug treated for 72 hrs by MTT assay | Homo sapiens | 30 | ALA3616466 | cell-based format | Scientific Literature | |
11. | ALA3618996 | F | Photocytotoxicity against human A549 cells assessed as inhibition of colony formation at 2.5 J/cm'2 irradiation after 1 to 2 weeks using crystal violet staining by optical microscopy | Homo sapiens | 4 | ALA3616466 | cell-based format | Scientific Literature | |
12. | ALA3618997 | F | Photocytotoxicity against human Jurkat cells assessed as reduction of cell survival at 0.2 uM measured 72 hrs post 2.5 J/cm'2 irradiation by MTT assay in the presence of vitamin E, NaN3, DABCO, DMTU and MANN | Homo sapiens | 1 | ALA3616466 | cell-based format | Scientific Literature | |
13. | ALA3618998 | P | Induction of singlet oxygen generation measured after UV-A irradiation by RNO bleaching assay | 2 | ALA3616466 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA3618999 | P | Induction of superoxide anion generation measured after UV-A irradiation by NBT reduction assay | 2 | ALA3616466 | small-molecule physicochemical format | Scientific Literature | ||
15. | ALA3619000 | F | Induction of apoptosis in human Jurkat cells assessed as reduction in alive cells using Annexin-V and propidium iodide staining at 1 to 2 uM measured 24 hrs post 2.5 J/cm'2 irradiation by flow cytometry analysis | Homo sapiens | 4 | ALA3616466 | cell-based format | Scientific Literature | |
16. | ALA3619001 | F | Induction of apoptosis in human Jurkat cells assessed as increase in cleaved caspase 3 level at 1 uM measured 24 hrs post 2.5 J/cm'2 irradiation by Western blot analysis | Homo sapiens | 4 | ALA3616466 | cell-based format | Scientific Literature | |
17. | ALA3619002 | F | Induction of apoptosis in human Jurkat cells assessed as reduction in mitochondrial potential at 1 to 2 uM using JC-1 staining measured 24 hrs post 2.5 J/cm'2 irradiation by FACS assay | Homo sapiens | 4 | ALA3616466 | cell-based format | Scientific Literature | |
18. | ALA3619003 | F | Induction of apoptosis in human Jurkat cells assessed as ROS production at 1 to 2 uM using HE and DCFDA staining measured 24 hrs post 2.5 J/cm'2 irradiation by FACS assay | Homo sapiens | 4 | ALA3616466 | cell-based format | Scientific Literature | |
19. | ALA3619004 | F | Induction of apoptosis in human Jurkat cells assessed as lysosome death at 1 to 2 uM using acridine orange staining measured 24 hrs post 2.5 J/cm'2 irradiation by flow cytometry | Homo sapiens | 4 | ALA3616466 | cell-based format | Scientific Literature | |
20. | ALA3619005 | B | Induction of DNA damage in Escherichia coli pBR322 DNA measured at 7.5 J/cm'2 UV-A irradiation by neutral agarose electrophoresis | Escherichia coli | 4 | ALA3616466 | assay format | Scientific Literature |