| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3620653 | B | Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 2. | ALA3620655 | F | Growth inhibition of human HL60 cells at 10 uM incubated for 48 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 3. | ALA3620656 | F | Growth inhibition of human HL60 cells at 10 uM incubated for 48 hrs in presence of 0.1 uM ATRA by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 4. | ALA3620658 | F | Induction of cell differentiation in human HL60 cells at 10 uM incubated for 72 hrs by NBT dye based assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 5. | ALA3620659 | F | Induction of cell differentiation in human HL60 cells at 10 uM incubated for 72 hrs in presence of 0.1 uM ATRA by NBT dye based assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 6. | ALA3620660 | A | Inhibition of CYP3A4 (unknown origin) incubated for 45 mins using NADPH by fluorescence assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 7. | ALA3620661 | A | Inhibition of CYP2D6 (unknown origin) incubated for 45 mins using NADPH and ATRA by HPLC assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 8. | ALA3620662 | U | Selectivity index, ratio of IC50 for CYP3A4 (unknown origin) to IC50 for CYP26A1 in ATRA-induced human HL60 cell microsomes | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3620663 | U | Selectivity index, ratio of IC50 for CYP2D6 (unknown origin) to IC50 for CYP26A1 in ATRA-induced human HL60 cell microsomes | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3620664 | B | Inhibition of CYP26A1-mediated ATRA metabolism in human HL60 cells assessed as ATRA level at 5 uM incubated for 24 hrs by HPLC method (Rvb = 7.19 uM) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA3620665 | B | Inhibition of CYP26A1-mediated ATRA metabolism in human HL60 cells assessed as ATRA level at 5 uM incubated for 48 hrs by HPLC method (Rvb = 4.95 uM) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA3620666 | B | Inhibition of CYP26A1-mediated ATRA metabolism in human HL60 cells assessed as ATRA level at 5 uM incubated for 72 hrs by HPLC method (Rvb = 3.6 uM) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA3620667 | B | Inhibition of CYP26A1-mediated ATRA metabolism in human HL60 cells assessed as ATRA level at 5 uM incubated for 96 hrs by HPLC method (Rvb = 1.21 uM) | Homo sapiens | 2 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!