# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3619823 | B | Inhibition of gamma-secretase in rat primary neuronal cells assessed as reduction in amyloid beta (1 to 42) production | Rattus norvegicus | 20 | cell-based format | Scientific Literature | ||
2. | ALA3620356 | P | Lipophilicity, log D of the compound at pH 7.4 by reversed phase chromatography | 20 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA3620357 | B | Inhibition of gamma-secretase in rat primary neuronal cells assessed as reduction in amyloid beta (1 to 40) production | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
4. | ALA3620358 | A | Inhibition of gamma-secretase-mediated Notch processing in rat primary neuronal cells | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
5. | ALA3620359 | A | Drug level in C57BL/6J mouse cortex at 10 mg/kg, po after 3 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
6. | ALA3620360 | A | Drug level in C57BL/6J mouse plasma at 10 mg/kg, po after 3 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
7. | ALA3620361 | F | Reduction in amyloid beta (1 to 42) levels in C57BL/6J mouse brain at 10 mg/kg, po after 3 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA3620362 | F | Reduction in amyloid beta (1 to 40) levels in C57BL/6J mouse brain at 10 mg/kg, po after 3 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
9. | ALA3620363 | F | Reduction in amyloid beta (1 to 42) levels in C57BL/6J mouse plasma at 10 mg/kg, po after 3 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
10. | ALA3620364 | F | Reduction in amyloid beta (1 to 40) levels in C57BL/6J mouse plasma at 10 mg/kg, po after 3 hrs | Mus musculus | 1 | organism-based format | Scientific Literature |