# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3624287 | F | Anticonvulsant activity in sc dosed Sprague-Dawley rat assessed as protection against maximal electroshock-induced convulsion administered 30 mins prior to application of shock via corneal electrodes | Rattus norvegicus | 1 | ALA3621090 | organism-based format | Scientific Literature | |
2. | ALA3624288 | B | Activation of human Kv7.2/7.3 expressed in CHOK1 cells | Homo sapiens | 17 | ALA3621090 | cell-based format | Scientific Literature | |
3. | ALA3624289 | B | Activation of human Kv7.4 expressed in CHOK1 cells | Homo sapiens | 1 | ALA3621090 | cell-based format | Scientific Literature | |
4. | ALA3624290 | B | Activation of human Kv7.2/7.3 expressed in CHOK1 cells assessed as increase in current amplitude relative to control | Homo sapiens | 1 | ALA3621090 | cell-based format | Scientific Literature | |
5. | ALA3624291 | B | Activation of human Kv7.3/7.5 expressed in CHOK1 cells | Homo sapiens | 1 | ALA3621090 | cell-based format | Scientific Literature | |
6. | ALA3624292 | B | Activation of human Kv7.1/KCNE1 expressed in CHOK1 cells | Homo sapiens | 1 | ALA3621090 | cell-based format | Scientific Literature | |
7. | ALA3624293 | B | Activation of rat Kv7.2/7.3 expressed in CHOK1 cells | Rattus norvegicus | 1 | ALA3621090 | cell-based format | Scientific Literature | |
8. | ALA3624294 | B | Activation of rat Kv7.4 expressed in CHOK1 cells | Rattus norvegicus | 1 | ALA3621090 | cell-based format | Scientific Literature | |
9. | ALA3624295 | B | Activation of rat Kv7.3/7.5 expressed in CHOK1 cells | Rattus norvegicus | 1 | ALA3621090 | cell-based format | Scientific Literature | |
10. | ALA3624296 | B | Activation of human Kv7.4 expressed in CHOK1 cells assessed as increase in current amplitude relative to control | Homo sapiens | 1 | ALA3621090 | cell-based format | Scientific Literature | |
11. | ALA3624297 | B | Activation of human Kv7.3/7.5 expressed in CHOK1 cells assessed as increase in current amplitude relative to control | Homo sapiens | 1 | ALA3621090 | cell-based format | Scientific Literature | |
12. | ALA3624298 | B | Activation of human Kv7.1/KCNE1 expressed in CHOK1 cells assessed as increase in current amplitude relative to control | Homo sapiens | 1 | ALA3621090 | cell-based format | Scientific Literature | |
13. | ALA3626772 | B | Activation of rat Kv7.2/7.3 expressed in CHOK1 cells assessed as increase in current amplitude relative to control | Rattus norvegicus | 1 | ALA3621090 | cell-based format | Scientific Literature | |
14. | ALA3626773 | B | Activation of rat Kv7.4 expressed in CHOK1 cells assessed as increase in current amplitude relative to control | Rattus norvegicus | 1 | ALA3621090 | cell-based format | Scientific Literature | |
15. | ALA3626774 | B | Activation of rat Kv7.3/7.5 expressed in CHOK1 cells assessed as increase in current amplitude relative to control | Rattus norvegicus | 1 | ALA3621090 | cell-based format | Scientific Literature | |
16. | ALA3626775 | A | Intrinsic clearance in human liver microsomes measured over 1 hr in presence of NADPH regenerating system | Homo sapiens | 9 | ALA3621090 | assay format | Scientific Literature | |
17. | ALA3626776 | A | Permeability in dog RRCK cells after 2 hrs by transwell assay | Canis lupus familiaris | 10 | ALA3621090 | cell-based format | Scientific Literature | |
18. | ALA3626777 | A | Efflux ratio of permeability from apical to basolateral over basolateral to apical side in MDCK cells transfected with MDR1 | Canis lupus familiaris | 9 | ALA3621090 | cell-based format | Scientific Literature | |
19. | ALA3626778 | T | Toxicity in human THLE cells assessed as ATP depletion | Homo sapiens | 10 | ALA3621090 | cell-based format | Scientific Literature | |
20. | ALA3626780 | A | Unbound plasma concentration in Sprague-Dawley rat at 1 mg/kg, sc administered at 30 mins by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA3621090 | organism-based format | Scientific Literature |