# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3626888 | Binding | Inhibition of recombinant human KAT2B catalytic domain using biotinylated histone H3 (1 to 21 amino acid residues) as substrate at 50 uM preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay | Homo sapiens | 28 | ALA3621044 | single protein format | Scientific Literature | |
2. | ALA3626889 | Binding | Inhibition of recombinant human KAT2B catalytic domain using biotinylated histone H3 (1 to 21 amino acid residues) as substrate preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay | Homo sapiens | 22 | ALA3621044 | single protein format | Scientific Literature | |
3. | ALA3626890 | Binding | Inhibition of recombinant human KAT2A using biotinylated histone H3 (1 to 21 amino acid residues) as substrate at 50 uM preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay | Homo sapiens | 28 | ALA3621044 | single protein format | Scientific Literature | |
4. | ALA3626891 | Binding | Inhibition of recombinant human KAT2A using biotinylated histone H3 (1 to 21 amino acid residues) as substrate preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay | Homo sapiens | 21 | ALA3621044 | single protein format | Scientific Literature | |
5. | ALA3626892 | Binding | Inhibition of recombinant human CBP using biotinylated histone H3 (1 to 21 amino acid residues) as substrate at 50 uM preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay | Homo sapiens | 15 | ALA3621044 | single protein format | Scientific Literature | |
6. | ALA3626894 | Binding | Inhibition of recombinant human p300 using biotinylated histone H3 (1 to 21 amino acid residues) as substrate at 50 uM preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay | Homo sapiens | 28 | ALA3621044 | single protein format | Scientific Literature | |
7. | ALA3626897 | Functional | Cytotoxicity against human LNCAP cells assessed as growth inhibition after 72 hrs by MTS assay | Homo sapiens | 6 | ALA3621044 | cell-based format | Scientific Literature | |
8. | ALA3626898 | Functional | Cytotoxicity against human HL60 cells assessed as growth inhibition after 72 hrs by MTS assay | Homo sapiens | 7 | ALA3621044 | cell-based format | Scientific Literature |