# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3626195 | B | Binding affinity to Nedd4 (unknown origin) assessed as reduction in PPxY-Nedd4 protein interaction | Homo sapiens | 1 | ALA3621082 | single protein format | Scientific Literature | |
2. | ALA3830397 | B | Inhibition of Marburg virus VP40 PPxY L-domain motif expressed in HEK293T cells assessed as reduction in VLP budding at 1 uM relative to control | Marburgvirus | 31 | ALA3826909 | cell-based format | Scientific Literature | |
3. | ALA3830403 | B | Inhibition of Marburg virus VP40 PPxY L-domain motif expressed in HEK293T cells assessed as reduction in VLP budding at 1 uM after 24 hrs by Western blot analysis relative to control | Marburgvirus | 1 | ALA3826909 | cell-based format | Scientific Literature | |
4. | ALA3830716 | A | Half life in mouse liver microsomes | Mus musculus | 8 | ALA3826909 | tissue-based format | Scientific Literature | |
5. | ALA3830717 | A | Intrinsic clearance in mouse liver microsomes assessed per mg of protein | Mus musculus | 8 | ALA3826909 | tissue-based format | Scientific Literature | |
6. | ALA3830720 | A | Half life in human liver microsomes | Homo sapiens | 8 | ALA3826909 | tissue-based format | Scientific Literature | |
7. | ALA3830721 | A | Intrinsic clearance in human liver microsomes assessed per mg of protein | Homo sapiens | 8 | ALA3826909 | tissue-based format | Scientific Literature | |
8. | ALA3830722 | A | Inhibition of CYP3A4 (unknown origin) using midazolam as substrate | Homo sapiens | 8 | ALA3826909 | single protein format | Scientific Literature | |
9. | ALA4495582 | F | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
10. | ALA4513082 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 |