# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3624416 | B | Displacement of [3H](+)-pentazocine from sigma-1 receptor in guinea pig brain cortex after 120 mins by scintillation counting analysis | Cavia porcellus | 18 | assay format | Scientific Literature | ||
2. | ALA3624417 | B | Displacement of [3H]-DTG from sigma-2 receptor in Sprague-Dawley rat liver membranes after 120 mins by scintillation counting analysis | Rattus norvegicus | 18 | cell membrane format | Scientific Literature | ||
3. | ALA4267897 | B | Displacement of [3H](+)-pentazocine from S1R in guinea pig brain cortex membranes after 120 mins by scintillation counting assay | Cavia porcellus | 26 | cell membrane format | Scientific Literature | ||
4. | ALA4267898 | B | Displacement of [3H]-DTG from S2R in rat liver membranes after 120 mins by scintillation counting assay | Rattus norvegicus | 26 | cell membrane format | Scientific Literature | ||
5. | ALA4267899 | B | Selectivity ratio of Ki for S2R in rat liver membranes to Ki for S2R in guinea pig brain cortex membranes | 21 | cell membrane format | Scientific Literature | |||
6. | ALA4267901 | B | Inhibition of electric eel AChE at 50 uM using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Ellman's method relative to control | Electrophorus electricus | 24 | single protein format | Scientific Literature | ||
7. | ALA4267902 | B | Displacement of [3H]-ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by scintillation counting analysis | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
8. | ALA4267907 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 10 uM after 24 hrs by MTS assay relative to control | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
9. | ALA4267908 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 25 uM after 24 hrs by MTS assay relative to control | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
10. | ALA4267909 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 50 uM after 24 hrs by MTS assay relative to control | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
11. | ALA4267910 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 10 uM after 48 hrs by MTS assay relative to control | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
12. | ALA4267911 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 25 uM after 48 hrs by MTS assay relative to control | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
13. | ALA4267912 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 50 uM after 48 hrs by MTS assay relative to control | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
14. | ALA4267913 | F | Neuroprotection against H2O2-induced oxidative stress in human SH-SY5Y cells assessed as reduction in ROS generation at 10 uM preincubated for 3 hrs followed by DCFDA addition for 45 mins and subsequent co-treatment with compound and H2O2 for 24 hrs by fluorescence assay relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
15. | ALA5232469 | B | Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method | Cavia porcellus | 9 | cell membrane format | Scientific Literature | ||
16. | ALA5232471 | T | Cytotoxicity against rat PC-12 cells assessed as cell death at 0.25 uM after 72 hrs incubation by LDH-based cytotoxic assay | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
17. | ALA5232472 | F | Neuroprotective activity in rat PC-12 cells assessed as increase in NGF-mediated neurite outgrowth by measuring differentiated cells at 5 to 250 nM incubated for 72 hrs by bright-field microscopic analysis | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
18. | ALA5232473 | F | Neuroprotective activity in rat PC-12 cells assessed as increase in NGF-mediated neurite outgrowth by measuring differentiated cells at 5 to 250 nM in presence of 1 uM NE-100 incubated for 72 hrs by bright-field microscopic analysis | Rattus norvegicus | 4 | cell-based format | Scientific Literature |