# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3626367 | B | Agonist activity at wild type AR expressed in human SC cells assessed as effect on cell proliferation by WST-8 assay | Homo sapiens | 30 | ALA3621051 | cell-based format | Scientific Literature | |
2. | ALA3626368 | B | Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 1 nM DHT-induced cell proliferation after 3 days by WST-8 assay | Homo sapiens | 30 | ALA3621051 | cell-based format | Scientific Literature | |
3. | ALA3626369 | B | Antagonist activity at wild type AR expressed in human SC cells assessed as inhibition of 0.3 to 10 nM DHT-induced cell proliferation after 3 days by WST-8 assay | Homo sapiens | 2 | ALA3621051 | cell-based format | Scientific Literature | |
4. | ALA3626370 | B | Displacement of [3H]-DHT from human GST fused AR-LBD (627 to 919 amino acids) transfected in Escherichia coli HB 101 after 15 hrs by liquid scintillation counting assay | Homo sapiens | 7 | ALA3621051 | assay format | Scientific Literature | |
5. | ALA3626371 | B | Antagonist activity at AR T877A mutant expressed in human LNCaP cells assessed as inhibition of 10 nM DHT-stimulated cell proliferation after 6 days by WST-8 assay | Homo sapiens | 7 | ALA3621051 | cell-based format | Scientific Literature | |
6. | ALA3626372 | B | Antagonist activity at AR T877A mutant expressed in human LNCaP cells assessed as inhibition of 10 nM testosterone-induced PSA production after 48 hrs by ELISA method | Homo sapiens | 7 | ALA3621051 | cell-based format | Scientific Literature | |
7. | ALA3624442 | F | Cytotoxicity against androgen-independent human PC3 cells assessed as inhibition of cell proliferation after 3 days by WST-8 assay | Homo sapiens | 6 | ALA3621051 | cell-based format | Scientific Literature | |
8. | ALA5140935 | F | Antiproliferative activity against human LNCaP cells | Homo sapiens | 9 | ALA5137058 | cell-based format | Scientific Literature | |
9. | ALA5140965 | F | Antiproliferative activity against mouse SC-3 cells | Mus musculus | 3 | ALA5137058 | cell-based format | Scientific Literature | |
10. | ALA5140966 | B | Antagonist activity at Androgen receptor in human LNCaP cells assessed as inhibition of PSA expression | Homo sapiens | 5 | ALA5137058 | cell-based format | Scientific Literature |