| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3624213 | B | Transrepression activity of LXR in human THP1 cells assessed as inhibition of LPS-induced IL-6 level at 10 uM after 18 hrs by ELISA | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 2. | ALA3624216 | B | Agonist activity at human LXR-alpha transfected in HEK293 cells at 30 uM after 16 hrs by luciferase reporter gene assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 3. | ALA3624218 | B | Agonist activity at human LXR-beta transfected in HEK293 cells at 30 uM after 16 hrs by luciferase reporter gene assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 4. | ALA3624220 | B | Antagonist activity at human LXR-alpha transfected in HEK293 cells after 16 hrs by luciferase reporter gene assay in presence of 0.3 uM N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-(2,2,2-trifluoroethyl)benzenesulfonamide | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 5. | ALA3624222 | B | Antagonist activity at human LXR-beta transfected in HEK293 cells after 16 hrs by luciferase reporter gene assay in presence of 0.1 uM N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-(2,2,2-trifluoroethyl)benzenesulfonamide | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 6. | ALA3624223 | B | Antagonist activity at human LXR-beta transfected in HEK293 cells at 30 uM after 16 hrs by luciferase reporter gene assay in presence of 0.1 uM N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-(2,2,2-trifluoroethyl)benzenesulfonamide | Homo sapiens | 19 | cell-based format | Scientific Literature |
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