# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3627546 | F | Growth inhibition of human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue dye based florescence assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
2. | ALA3627547 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as increase in caspase-3/7 activity incubated for 24 hrs by luminescence based assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
3. | ALA3626423 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as increase in caspase-3/7 activity incubated for 24 hrs by luminescence based assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA3626424 | A | Half life in C57BL/6 mouse plasma at 10 mg/kg, sc by LC/MS method | Mus musculus | 2 | organism-based format | Scientific Literature | ||
5. | ALA3626425 | A | Half life in C57BL/6 mouse plasma at 10 mg/kg, po by LC/MS method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
6. | ALA3626426 | A | Stability in mouse plasma incubated at 37 degC by LC/MS method | Mus musculus | 2 | cell-free format | Scientific Literature | ||
7. | ALA3626427 | A | Stability in mouse plasma assessed as intact compound level incubated for 144 hrs incubated at 37 degC by LC/MS method | Mus musculus | 2 | cell-free format | Scientific Literature | ||
8. | ALA3626428 | F | Anticancer activity against human MDA-MB-231 cells xenografted in BALB/SCID gnotobiotic mouse assessed as reduction in tumor volume at 2.5 to 15 mg/kg, sc dosed total of 10 doses on days 1 to 5 and 8 to 12 | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
9. | ALA3626429 | A | Bioavailability in human MDA-MB-231 cells xenografted BALB/SCID gnotobiotic mouse at 2.5 to 15 mg/kg, sc dosed total of 10 doses on days 1 to 5 and 8 to 12 | Mus musculus | 1 | organism-based format | Scientific Literature | ||
10. | ALA3626430 | F | Anticancer activity against human MDA-MB-231 cells xenografted in BALB/SCID gnotobiotic mouse assessed as time duration for tumor growth delay at 500 mm3 at 2.5 mg/kg, sc dosed total of 10 doses on days 1 to 5 and 8 to 12 | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
11. | ALA3626431 | F | Anticancer activity against human MDA-MB-231 cells xenografted in BALB/SCID gnotobiotic mouse assessed as time duration for tumor growth delay at 500 mm3 at 7.5 mg/kg, sc dosed total of 10 doses on days 1 to 5 and 8 to 12 | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
12. | ALA3626432 | F | Anticancer activity against human MDA-MB-231 cells xenografted in BALB/SCID gnotobiotic mouse assessed as time duration for tumor growth delay at 500 mm3 at 15 mg/kg, sc dosed total of 10 doses on days 1 to 5 and 8 to 12 | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
13. | ALA3626433 | F | Anticancer activity against human MDA-MB-231 cells xenografted in BALB/SCID gnotobiotic mouse assessed as time duration for tumor growth delay at 500 mm3 at 30 mg/kg, po dosed total of 10 doses on days 1 to 5 and 8 to 12 | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
14. | ALA4700869 | F | Antiproliferative activity against human BTTR cells assessed as growth inhibition after 48 hrs by PrestoBlue dye based fluorescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
15. | ALA4700870 | F | Antiproliferative activity against human BT-474 cells assessed as growth inhibition after 48 hrs by PrestoBlue dye based fluorescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
16. | ALA4700871 | F | Antiproliferative activity against human HCC1954 cells assessed as growth inhibition after 48 hrs by PrestoBlue dye based fluorescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
17. | ALA4700872 | F | Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by PrestoBlue dye based fluorescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
18. | ALA4700873 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 48 hrs by PrestoBlue dye based fluorescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
19. | ALA4700874 | F | Antiproliferative activity against human MDA-MB-361 cells assessed as growth inhibition after 48 hrs by PrestoBlue dye based fluorescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
20. | ALA4700875 | F | Antiproliferative activity against human T47D cells assessed as growth inhibition after 48 hrs by PrestoBlue dye based fluorescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature |