# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3625050 | Functional | Antioxidant activity in rat heat-inactivated rat hepatic microsomes assessed as inhibition of TBAR level incubated for 45 mins by spectrophotometry | Rattus norvegicus | 17 | ALA3621067 | assay format | Scientific Literature | |
2. | ALA3625051 | Binding | Inhibition of squalene synthase in rat liver microsomes assessed as reduction in conversion of [3H]farnesyl pyrophosphate to squalene at 10 uM incubated for 30 mins by liquid scintillation counting method | Rattus norvegicus | 14 | ALA3621067 | assay format | Scientific Literature | |
3. | ALA3625053 | Functional | Antihyperlipidemic activity in Triton WR1339-induced hyperlipidemic rat assessed as reduction in plasma total cholesterol at 56 umol/kg, ip dosed 1 hr after Triton WR1339 challenge and measured 24 hrs post dose relative to control | Rattus norvegicus | 18 | ALA3621067 | organism-based format | Scientific Literature | |
4. | ALA3625054 | Functional | Antihypercholesterolemic activity in Triton WR1339-induced hyperlipidemic rat assessed as reduction in plasma LDL-C level at 56 umol/kg, ip dosed 1 hr after Triton WR1339 challenge and measured 24 hrs post dose relative to control | Rattus norvegicus | 18 | ALA3621067 | organism-based format | Scientific Literature | |
5. | ALA3625055 | Functional | Antihyperlipidemic activity in Triton WR1339-induced hyperlipidemic rat assessed as reduction in plasma triglyceride level at 56 umol/kg, ip dosed 1 hr after Triton WR1339 challenge and measured 24 hrs post dose relative to control | Rattus norvegicus | 18 | ALA3621067 | organism-based format | Scientific Literature | |
6. | ALA3625056 | Binding | Inhibition of squalene synthase in rat liver microsomes assessed as reduction in conversion of [3H]farnesyl pyrophosphate to squalene incubated for 30 mins by liquid scintillation counting | Rattus norvegicus | 6 | ALA3621067 | assay format | Scientific Literature |