| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3632013 | B | Inhibition of Stat3 dimer DNA binding activity in mouse NIH3T3/vSrc nuclear extract at 5 uM preincubated for 30 mins followed by addition of radiolabeled probe hSIE for 30 mins by EMSA | Mus musculus | 24 | single protein format | Scientific Literature | ||
| 2. | ALA3632014 | B | Inhibition of Stat1:Stat3 dimer DNA binding activity in EGF-stimulated mouse NIH3T3 nuclear extract expressing human EGFR assessed as residual activity at 5 uM preincubated for 30 mins followed by addition of radiolabeled probe hSIE for 30 mins by EMSA | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA3632015 | B | Inhibition of Stat3 dimer DNA binding activity in EGF-stimulated mouse NIH3T3 nuclear extract expressing human EGFR assessed as residual activity at 5 uM preincubated for 30 mins followed by addition of radiolabeled probe hSIE for 30 mins by EMSA | Mus musculus | 6 | single protein format | Scientific Literature | ||
| 4. | ALA3632016 | B | Inhibition of Stat1 dimer DNA binding activity in EGF-stimulated mouse NIH3T3 nuclear extract expressing human EGFR assessed as residual activity at 5 uM preincubated for 30 mins followed by addition of radiolabeled probe hSIE for 30 mins by EMSA | Mus musculus | 6 | single protein format | Scientific Literature | ||
| 5. | ALA3632017 | B | Inhibition of Stat5 dimer DNA binding activity in EGF-stimulated mouse NIH3T3 nuclear extract expressing human EGFR at 5 uM preincubated for 30 mins followed by addition of radiolabeled probe MGFe for 30 mins by EMSA | Mus musculus | 11 | cell-based format | Scientific Literature | ||
| 6. | ALA3632018 | B | Inhibition of Stat1 dimer DNA binding activity in EGF-stimulated mouse NIH3T3 nuclear extract expressing human EGFR at 5 uM preincubated for 30 mins followed by addition of radiolabeled probe hSIE for 30 mins by EMSA | Mus musculus | 12 | single protein format | Scientific Literature | ||
| 7. | ALA3632022 | B | Inhibition of Stat3 activity in human U251MG cells assessed as phosphorylated Stat3 level at 5 uM by immunoblot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 8. | ALA3632141 | B | Modulation of EGF-induced Stat1 phosphorylation in mouse NIH3T3 cells expressing human EGFR at 5 uM preincubated for 3 hrs followed by stimulation with 1 ug/ml EGF for 12 mins by immunoblot analysis | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA3632142 | B | Modulation of EGF-induced Stat5 phosphorylation in mouse NIH3T3 cells expressing human EGFR at 5 uM preincubated for 3 hrs followed by stimulation with 1 ug/ml EGF for 12 mins by immunoblot analysis | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA3632143 | B | Modulation of EGF-induced Erk1/2 phosphorylation in mouse NIH3T3 cells expressing human EGFR at 5 uM preincubated for 3 hrs followed by stimulation with 1 ug/ml EGF for 12 mins by immunoblot analysis | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA3632144 | B | Inhibition of EGF-induced Stat3 phosphorylation in mouse NIH3T3 cells expressing human EGFR at 5 uM preincubated for 3 hrs followed by stimulation with 1 ug/ml EGF for 12 mins by immunoblot analysis | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA3632145 | B | Modulation of Akt phosphorylation in human U251MG cells at 5 uM after 0.5 to 24 hrs by immunoblot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA3632146 | B | Modulation of Erk1/2 phosphorylation in human U251MG cells at 5 uM after 0.5 to 24 hrs by immunoblot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 14. | ALA3632147 | F | Effect on SOCS3 expression in human U251MG cells at 5 uM after 0.5 to 24 hrs by immunoblot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA3632148 | F | Effect on PTP1B expression in human U251MG cells at 5 uM after 0.5 to 24 hrs by immunoblot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 16. | ALA3632149 | B | Inhibition of orthovandate-induced Stat3 phosphorylation in human U251MG cells at 5 uM for 3 hrs by immunoblot analysis in presence of 10 to 300 uM orthovandate | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 17. | ALA3632157 | F | Antiproliferative activity against human U251MG cells for 72 hrs by cyquant assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 18. | ALA3632158 | F | Antiproliferative activity against human MDA-MB-231 cells for 72 hrs by cyquant assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 19. | ALA3632159 | F | Antiproliferative activity against human U373MG cells for 72 hrs by cyquant assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 20. | ALA3632160 | F | Antiproliferative activity against human SF295 cells for 72 hrs by cyquant assay | Homo sapiens | 5 | cell-based format | Scientific Literature |
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