# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3632250 | B | Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Homo sapiens | 5 | ALA3627626 | cell-based format | Scientific Literature | |
2. | ALA3632251 | A | Cytotoxicity against PCFT-null Chinese hamster R2 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Cricetulus griseus | 5 | ALA3627626 | cell-based format | Scientific Literature | |
3. | ALA3632252 | B | Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Homo sapiens | 5 | ALA3627626 | cell-based format | Scientific Literature | |
4. | ALA3632253 | B | Binding affinity to human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay in presence of 200 nM folic acid | Homo sapiens | 5 | ALA3627626 | cell-based format | Scientific Literature | |
5. | ALA3632254 | B | Binding affinity to human FRbeta expressed in Chinese hamster D4 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Homo sapiens | 5 | ALA3627626 | cell-based format | Scientific Literature | |
6. | ALA3632255 | B | Binding affinity to human FRbeta expressed in Chinese hamster D4 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay in presence of 200 nM folic acid | Homo sapiens | 5 | ALA3627626 | cell-based format | Scientific Literature | |
7. | ALA3632256 | B | Binding affinity to human PCFT expressed in Chinese hamster R2/PCFT4 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Homo sapiens | 5 | ALA3627626 | cell-based format | Scientific Literature | |
8. | ALA3632257 | A | Cytotoxicity against Chinese hamster R2 cells transfected with empty PCDNA3 assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Cricetulus griseus | 5 | ALA3627626 | cell-based format | Scientific Literature | |
9. | ALA3632258 | B | Ratio of IC50 for human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition in presence of folic acid to IC50 for human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition in absence of folic acid | Homo sapiens | 2 | ALA3627626 | cell-based format | Scientific Literature | |
10. | ALA3632259 | B | Ratio of IC50 for human FRbeta expressed in Chinese hamster D4 cells assessed as cell growth inhibition in presence of folic acid to IC50 for human FRbeta expressed in Chinese hamster D4 cells assessed as cell growth inhibition in absence of folic acid | Homo sapiens | 2 | ALA3627626 | cell-based format | Scientific Literature | |
11. | ALA3632260 | B | Selectivity ratio of IC50 for human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition to IC50 for human FRalpha expressed in Chinese hamster RT16 cells assessed as cell growth inhibition | Homo sapiens | 4 | ALA3627626 | cell-based format | Scientific Literature | |
12. | ALA3632261 | B | Selectivity ratio of IC50 for human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition to IC50 for human FRbeta expressed in Chinese hamster D4 cells assessed as cell growth inhibition | Homo sapiens | 4 | ALA3627626 | cell-based format | Scientific Literature | |
13. | ALA3632262 | B | Selectivity ratio of IC50 for human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition to IC50 for human PCFT expressed in Chinese hamster R2/PCFT4 cells assessed as cell growth inhibition | Homo sapiens | 4 | ALA3627626 | cell-based format | Scientific Literature | |
14. | ALA3632263 | B | Binding affinity to human PCFT expressed in Chinese hamster R2/PCFT4 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay in presence of 200 nM folic acid | Homo sapiens | 5 | ALA3627626 | cell-based format | Scientific Literature | |
15. | ALA3632264 | F | Antiproliferative activity against human KB cells expressing FRalpha/PCFT/RFC assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Homo sapiens | 5 | ALA3627626 | cell-based format | Scientific Literature | |
16. | ALA3632265 | F | Antiproliferative activity against human KB cells expressing FRalpha/PCFT/RFC assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay in presence of 200 nM folic acid | Homo sapiens | 5 | ALA3627626 | cell-based format | Scientific Literature | |
17. | ALA3632266 | F | Antiproliferative activity against human IGROV1 cells after 96 hrs by CellTiter-Blue assay | Homo sapiens | 2 | ALA3627626 | cell-based format | Scientific Literature | |
18. | ALA3632267 | F | Antiproliferative activity against human SKOV3 cells after 96 hrs by CellTiter-Blue assay | Homo sapiens | 2 | ALA3627626 | cell-based format | Scientific Literature | |
19. | ALA3632268 | F | Antiproliferative activity against human IGROV1 cells after 96 hrs by CellTiter-Blue assay in presence of 200 nM folic acid | Homo sapiens | 2 | ALA3627626 | cell-based format | Scientific Literature | |
20. | ALA3632269 | F | Antiproliferative activity against human SKOV3 cells after 96 hrs by CellTiter-Blue assay in presence of 200 nM folic acid | Homo sapiens | 2 | ALA3627626 | cell-based format | Scientific Literature |